Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Showing posts with label Dr. Sacco. Show all posts
Showing posts with label Dr. Sacco. Show all posts

Wednesday, July 3, 2024

Two researchers to receive first-ever Ralph L. Sacco Scholarships for Brain Health

 I see nothing here that even remotely suggests they are working on the only goal in stroke: 100% RECOVERY! As such they really need to change the criteria for the award.

Two researchers to receive first-ever Ralph L. Sacco Scholarships for Brain Health

Two researchers to receive first-ever Ralph L. Sacco Scholarships for Brain Health
American Academy of Neurology and American Heart Association award $150,000 scholarships to researchers from Texas, Connecticut

DALLAS and MINNEAPOLIS, July 2, 2024 — The American Academy of Neurology and the American Heart Association have awarded the first-ever Ralph L. Sacco Scholarships for Brain Health to two researchers, Patrick Devlin, Ph.D., of Houston, Texas, and Cyprien Rivier, M.D., M.Sc., of New Haven, Connecticut. Each will receive a $150,000 two-year scholarship to support continuing scientific research in brain health. Devlin and Rivier also receive the professional distinction of being named the inaugural “Sacco Scholars.”

The Ralph L. Sacco Scholarships in Brain Health, also known as the Sacco Scholars program, are made possible by a generous bequest to the American Academy of Neurology and the American Heart Association from the late Ralph L. Sacco, M.D., M.S., FAAN, FAHA. Sacco was the only neurologist to have served as president of both organizations. He passed away in 2023 from a brain tumor.

“For more than 20 years, Dr. Ralph Sacco served as a dedicated volunteer for the American Heart Association, particularly leading the acceleration of our investment into and emphasis on brain health. He was the first neurologist to ever serve as our volunteer president,” said Nancy Brown, the American Heart Association’s chief executive officer. “He had big ideas and put them into action in ways that improved and saved the lives of all people. One of his greatest joys was mentoring young scientists, boosting their careers the same way icons of previous generations did for him. I am so proud to be able to welcome our first-ever Sacco Scholars in memory of my very dear friend.”

“It was important to Dr. Ralph Sacco to support continued research in brain health because, as he said, each and every one of us only has one brain, and it is critical to keep it as healthy as possible,” said American Academy of Neurology President Carlayne E. Jackson, M.D., FAAN. “We look forward to the inaugural year of this scholarship program with the first two Sacco Scholars and the vital research they will do to help find ways for all of us to improve our brain health.”

“Ralph was a personal friend and mentor, and I am grateful that his legacy of influencing the careers of countless physicians, researchers and health care professionals will live on through this unique scholarship program,” said Mitchell S.V. Elkind, M.D., M.S., FAAN, FAHA, chief clinical science officer and past volunteer president of the American Heart Association. “These research projects will build upon his decades of work in saving and improving the lives of people with stroke and will break new ground in our knowledge of how vascular disease impacts cognitive decline, dementia and brain health more broadly. I look forward to seeing what our awardees learn about the mechanisms of brain aging, both before and after stroke. I know Ralph would have been very interested in their projects.”

“Physicians who had the privilege of training under my dear friend Dr. Ralph Sacco knew he was a remarkable human being with a kind and generous heart,” said Orly Avitzur, M.D., M.B.A., FAAN, immediate past president of the American Academy of Neurology. “With the Sacco Scholars program, his mentorship continues as we begin creating a community of researchers focused on brain health.”

Devlin is a postdoctoral research fellow in the Ritzel Lab at the University of Texas Health Science Center at Houston. He is being awarded the scholarship for his research on the after-effects of stroke, specifically how the brain may age more quickly after a stroke, including the aging process of immune cells in the brain. The goal of Devlin’s research is to increase understanding of cognitive decline and dementia after stroke so that new treatments can be developed for people who have had a stroke, resulting in fewer complications such as memory loss. This is especially important to improve long-term quality of life as more people are surviving strokes thanks to advances in stroke diagnosis, treatment and care.

Rivier is a postdoctoral research fellow in the Falcone Lab in the Department of Neurology at Yale University. A significant portion of his work is conducted in collaboration with the Sheth Lab and the Yale Center for Brain and Mind Health. He is being awarded the scholarship for his research on how biological age—as opposed to chronological age—impacts the brain. Rivier is exploring whether people with younger biological age are less likely to develop dementia and stroke. By gaining a better understanding of biological age, Rivier’s research could lead to finding better ways for people to take care of their brain, lowering the risk of major health problems so they can live longer, healthier lives.

Devlin and Rivier began their two-year research projects on July 1.

About the American Heart Association 

The American Heart Association is a relentless force for a world of longer, healthier lives. We are dedicated to ensuring equitable health in all communities. Through collaboration with numerous organizations, and powered by millions of volunteers, we fund innovative research, advocate for the public’s health and share lifesaving resources. The Dallas-based organization has been a leading source of health information for a century. During 2024 - our Centennial year - we celebrate our rich 100-year history and accomplishments. As we forge ahead into our second century of bold discovery and impact our vision is to advance health and hope for everyone, everywhere. Connect with us on heart.org, Facebook, X or by calling 1-800-AHA-USA1.    

About the American Academy of Neurology

The American Academy of Neurology is the world's largest association of neurologists and neuroscience professionals, with over 40,000 members. The AAN’s mission is to enhance member career fulfillment and promote brain health for all. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer's disease, stroke, concussion, epilepsy, Parkinson's disease, multiple sclerosis, headache and migraine. For more information about the American Academy of Neurology, visit AAN.com or find us on FacebookXInstagramLinkedIn and YouTube.

For Media Inquiries: 214-706-1173

AHA - Cathy Lewis: cathy.lewis@heart.org

AAN - Renee Tessman: rtessman@aan.com

For Public Inquiries: 1-800-AHA-USA1 (242-8721)

heart.org and stroke.org

Wednesday, February 8, 2023

10 leading stroke scientists to receive American Stroke Association honors, including the Ralph L. Sacco Outstanding Stroke Research Mentor Award

If anything here points to getting survivors 100% recovered I don't see it and these are not valid honors.  As far as I can tell Dr. Sacco did nothing to advance survivor recovery. They can't be leading scientists. LEADERS DELIVER STROKE RECOVERY!

Please point EXACTLY to the interventions Dr. Sacco initiated that got survivors fully recovered. I take no prisoners in advancing stroke recovery and exposing naked emperors. 

What is Dr. Sacco's impact factor in getting survivors recovered?

10 leading stroke scientists to receive American Stroke Association honors, including the Ralph L. Sacco Outstanding Stroke Research Mentor Award 

American Stroke Association International Stroke Conference 2023
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Embargoed until 8 a.m. CT/9 a.m. ET, Tuesday, February 7, 2023

DALLAS, February 7, 2023Ten scientists leading the way in stroke research will be recognized for their exceptional achievements during the American Stroke Association’s International Stroke Conference 2023, to be held in person in Dallas and virtually Feb. 7-10. The world’s premier meeting for researchers and clinicians is dedicated to the science of stroke and brain health.

The illustrious group of awardees includes four groundbreaking scientists who have devoted their careers to stroke research, including the recipient of the newly renamed Ralph L. Sacco Outstanding Stroke Research Mentor Award. The award was renamed to honor Dr. Sacco, a past president of the American Heart Association and American Stroke Association, who passed away on Jan. 17. The award honors Dr. Sacco’s exceptional contributions to the field of stroke research and to the Association, as well as his instrumental role as a leading stroke mentor throughout his career. Six more scientists will be honored for their notable new research.

The honorees are:

  • Cheryl Bushnell, M.D., M.H.S., FAHA, Wake Forest University School of Medicine in Winston Salem, North Carolina, will receive the Edgar J. Kenton III Lecture Award.
  • Cheryl Bushnell, M.D., M.H.S., FAHA, Wake Forest University School of Medicine in Winston Salem, North Carolina, also will receive the Ralph L. Sacco Outstanding Stroke Research Mentor Award.
  • Zena Vexler, Ph.D., University California San Francisco, Weill Institute for Neurosciences in San Francisco, will be awarded the Thomas Willis Lecture Award.
  • George Howard, Dr.P.H., University of Alabama at Birmingham School of Public Health, Birmingham, Alabama, will receive the David G. Sherman Lecture Award.
  • José Biller, M.D., FAHA, Loyola University Chicago Stritch School of Medicine, Loyola University Health System in Maywood, Illinois, will be honored with the William M. Feinberg Award for Excellence in Clinical Stroke.
  • Daniela Renedo, M.D., Yale School of Medicine in New Haven, Connecticut, will receive the Stroke Basic Science Award.
  • Shun-Ming Ting, M.Sc., University of Texas Health Science Center at Houston, will receive the Mordecai Y.T. Globus New Investigator Award.
  • Kyle Kern, M.D., M.S., National Institute of Neurological Disorders and Stroke, a division of the National Institutes of Health, in Bethesda, Maryland, will receive the Vascular Cognitive Impairment Award.
  • Brian Mac Grory, M.B., B.Ch., B.A.O., FAHA, Duke University School of Medicine in Durham, North Carolina, will receive the Stroke Care in Emergency Medicine Award.
  • Kent Simmonds, D.O., Ph.D., UT Southwestern Medical Center in Dallas, will be awarded the Stroke Rehabilitation Award.
  • Eva A. Mistry, M.B.B.S., M.S.C.I., FAHA, University of Cincinnati in Ohio, will receive this year’s Robert G. Siekert New Investigator Award in Stroke.

Cheryl Bushnell, M.D., M.H.S., FAHA, the winner of the Edgar J. Kenton III Lecture Award, is a professor of neurology, vice chair of research, Stroke Division chief and co-director of the Neuroscience Clinical Trial and Innovation Center at Wake Forest University School of Medicine in Winston Salem, North Carolina. Bushnell is passionate about inpatient and outpatient stroke treatment across the continuum, especially the transition of post-acute care and secondary prevention. Her research spans women’s issues related to stroke including sex differences in risk and outcomes. She also served as chair of the first AHA Guideline for the Prevention of Stroke in Women. The Edgar J. Kenton III Lecture Award recognizes lifetime contributions to the investigation, management, mentorship and community service in the field of racial and ethnic stroke disparities or related disciplines. Bushnell will present her Edgar J. Kenton III lecture, “Achieving BP Goals and Addressing Inequities in BP Management after Stroke: It All Starts with Stakeholder Engagement,at 9:30 a.m. CT, Tuesday, February 7.

Cheryl Bushnell, M.D., M.H.S., FAHA, also is the recipient of the newly renamed Ralph L. Sacco Outstanding Stroke Research Mentor Award. The Stroke Research Mentor Award recognizes outstanding achievements in mentoring future generations of stroke researchers in the field of cerebrovascular disease. Throughout her career, Bushnell has mentored undergraduate and medical students, neurology residents, stroke fellows, junior faculty and nurse practitioners on stroke research projects. Bushnell will present her lecture, “Stroke Research and Academic Learning Health Systems: Mentoring Challenges and Opportunities,” at 11:19 a.m. CT, Thursday, February 9.

Zena Vexler, Ph.D., the  winner of the Thomas Willis Lecture Award, is professor and director of research at the Neonatal Brain Disorders (NBD) Center in the department of neurology at the University California, San Francisco and Weill Institute for Neurosciences in San Francisco. The Thomas Willis Award recognizes contributions to the investigation and management of stroke basic science. Vexler’s research interests include the mechanisms of perinatal arterial ischemic stroke (PAIS) and childhood arterial ischemic stroke (CAIS), and how brain maturation at the time of stroke affects brain injury and repair. She has been an editorial board member for several journals, including Stroke, the Journal of Cerebral Blood Flow and Metabolism, Fluids and Barriers of the CNS and Pediatric Research. As laboratory director and director of research for the NBD Center, she has trained more than 30 post-doctoral fellows and physician scientists from around the world. Vexler’s lecture, Immune-neurovascular Interactions in Experimental Perinatal and Childhood Stroke,” will be presented at 11:30 a.m. CT, Wednesday, February 8.

George Howard, Dr.P.H., the winner of the David G. Sherman Lecture Award, is a Professor of Biostatistics at the University of Alabama at Birmingham. He received his training in biostatistics from the University of North Carolina at Chapel Hill. The Sherman Award honors David G. Sherman, M.D., a prominent stroke physician and an internationally recognized leader and researcher in stroke prevention and treatment. The award recognizes lifetime contributions to the investigation, management, mentorship and community service in the stroke field. Howard’s extensive experience includes biostatistics, cerebrovascular/cardiovascular epidemiology, data management and the direction of coordinating centers of multicenter studies. His career has a dual focus of observational studies in cardiovascular epidemiology (with a recent focus to understand and reduce disparities in stroke and other cardiovascular diseases), and in the direction of coordinating centers for multi-center, randomized clinical trials. Howard will present his lecture, Reducing the Disparities in Stroke. Have We Been Aiming at the Right Targets? at 11:02 a.m. CT, Thursday, February 9.

José Biller, M.D., FAHA, the awardee of the William M. Feinberg Award for Excellence in Clinical Stroke, is professor of neurology and neurological surgery and chairperson of the department of neurology at Loyola University Chicago’s Stritch School of Medicine at Loyola University Health System in Maywood, Illinois. The William M. Feinberg Award for Excellence in Clinical Stroke is named for the prominent stroke clinician-researcher and American Heart Association volunteer who contributed to a more comprehensive understanding of the causes of stroke. The award recognizes significant contributions to the investigation and management of clinical research in stroke. Biller is the recent past chief editor of the Journal of Stroke and Cerebrovascular Diseases, past chief editor of Frontiers in Neurology, and an editorial board member and reviewer for an array of other national and international journals and publications. He has published hundreds of peer-reviewed articles and book chapters and given more than 750 lectures around the world. Biller’s lecture, “Identifying Stroke Mimics, Chameleons, and Beyond: A visual overview,” will be presented at 11:02 a.m. CT, Friday, February 10.

Daniela Renedo, M.D., the winner of the Stroke Basic Science Award, is a postdoctoral research fellow working in the departments of neurosurgery and neurology at the Yale School of Medicine in New Haven, Connecticut, co-mentored by Dr. Charles Matouk and Dr. Guido Falcone. She completed her medical degree at Austral University School of Medicine followed by neurosurgery residency at the Hospital de Clinicas “Jose de San Martin,” both in Buenos Aires, Argentina. Then, she emigrated to the United States to pursue advanced research training in population genetics, genomic medicine, data sciences and single-cell analysis. Supported by a grant from the American Heart Association, Renedo’s work focuses on understanding the socioeconomic and biological underpinnings of neurovascular diseases. The Stroke Basic Science Award recognizes outstanding basic or translational science that is laboratory-based. Renedo’s winning presentation (Abstract 15), “Single-cell Immune Landscape of Human Clot Retrieved at Mechanical Thrombectomy: Association with Stroke Origin,” will be presented at 7:30 a.m. CT, Wednesday, February 8.

Shun-Ming Ting, M.Sc., the Mordecai Y.T. Globus New Investigator Award in Stroke winner, is a Ph.D. student in neuroimmunology at the University of Texas Health Science Center at Houston. This award recognizes Globus’ major contributions to research in cerebrovascular disease and his outstanding contributions to the elucidation of the role of neurotransmitters in ischemia and trauma; the interactions among multiple neurotransmitters; mechanisms of hypothermic neuroprotection; and the role of oxygen radical mechanisms and nitric oxide in brain injury. Ting’s award-winning presentation (Abstract 16), “Retinoid X Receptors (RXR) Play Essential Roles in Improving Post-ischemic Stroke Recovery in Aged Brain by Restoring Age-associated Dysfunctions of Microglia/macrophages” will be presented at 7:42 a.m. CT, Wednesday, February 8.

Kyle Kern, M.D., M.S., is the Vascular Cognitive Impairment Award recipient. He is  a clinical research fellow in the intramural stroke branch of the National Institute of Neurological Disorders and Stroke, a division of the National Institutes of Health in Bethesda, Maryland. The Vascular Cognitive Impairment Award encourages investigators to undertake or continue research or clinical work in the field of vascular cognitive impairment and submit an abstract to the International Stroke Conference. Kern’s award-winning presentation (Abstract 55), “Intensive Blood Pressure Treatment Remodels Brain Perivascular Spaces: A Secondary Analysis of The SPRINT MIND Trial, will be presented at 3:30 p.m. CT, Wednesday, February 8.

Brian Mac Grory, M.B., B.Ch., B.A.O., FAHA, the winner of the Stroke Care in Emergency Medicine Award, is an associate professor of neurology & ophthalmology at Duke University School of Medicine in Durham, North Carolina. The Stroke Care in Emergency Medicine Award encourages investigators to undertake or continue research in the emergent phase of acute stroke treatment and submit an abstract to the International Stroke Conference. Mac Grory’s winning presentation (Abstract 67), “Endovascular Thrombectomy in Patients with Acute Ischemic Stroke and Recent Use of Oral Vitamin K-Antagonists: The Get With The Guidelines-Stroke Program” will be presented at 7:30 a.m. CT, Thursday, February 9.

Kent Simmonds, D.O., Ph.D., the  Stroke Rehabilitation Award winner, is a second-year resident at UT Southwestern Medical Center in Dallas, Texas. The Stroke Rehabilitation Award encourages investigators to undertake or continue research and/or clinical work in the field of stroke rehabilitation. Simmonds’ winning presentation (Abstract 146), “Racial Disparities in The Treatment of Post-stroke Complications Among Acute Stroke Patients,” will be presented at 9:15 a.m. CT, Friday, February 10.

Eva A. Mistry, M.B.B.S., M.S.C.I., FAHA, the winner of the Robert G. Siekert New Investigator Award in Stroke, is an assistant professor of clinical neurology and rehabilitation medicine at the University of Cincinnati in Ohio. The Siekert New Investigator Award in Stroke recognizes Robert G. Siekert, who was the founding chairman of the American Heart Association’s International Conference on Stroke and Cerebral Circulation, now known as the International Stroke Conference. The award encourages new investigators to undertake or continue stroke-related research. Mistry’s award-winning presentation (Abstract LB18), Blood Pressure After Endovascular Stroke Treatment (BEST)-II: A Randomized Clinical,” will be presented at 11:17 a.m. CT, Friday, February 10.

Statements and conclusions of studies presented at the American Heart Association’s scientific meetings are solely those of the study authors and do not necessarily reflect the Association’s policies or positions. The Association makes no representation or guarantee as to their accuracy or reliability. Abstracts presented at the Association’s scientific meetings are not peer-reviewed; rather, they are curated by independent review panels and are considered based on the potential to add to the diversity of scientific issues and views discussed at the meeting. The findings are considered preliminary until published as a full manuscript in a peer-reviewed scientific journal.

The Association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific Association programs and events. The Association has strict policies to prevent these relationships from influencing science content. Revenues from pharmaceutical and biotech companies, device manufacturers and health insurance providers and the Association’s overall financial information are available here.

Additional Resources:

The American Stroke Association’s International Stroke Conference (ISC) is the world’s premier meeting dedicated to the science and treatment of cerebrovascular disease. ISC 2023 will be held in person in Dallas and virtually, Feb. 8-10, 2023. The three-day conference will feature more than a thousand compelling presentations in categories that emphasize basic, clinical and translational sciences as research evolves toward a better understanding of stroke pathophysiology with the goal of developing more effective therapies. Engage in the International Stroke Conference on social media via #ISC23.

About the American Stroke Association

The American Stroke Association is devoted to saving people from stroke — the No. 2 cause of death in the world and a leading cause of serious disability. We team with millions of volunteers to fund innovative research, fight for stronger public health policies and provide lifesaving tools and information to prevent and treat stroke. The Dallas-based association officially launched in 1998 as a division of the American Heart Association. To learn more or to get involved, call 1-888-4STROKE or visit stroke.org. Follow us on Facebook, Twitter.

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For Media Inquiries and AHA Expert Perspective:

AHA Communications & Media Relations in Dallas: 214-706-1173; ahacommunications@heart.org

Saturday, January 21, 2023

Renowned neurologist Ralph L. Sacco remembered for leadership, advancements in stroke

 Really? Please point EXACTLY to the interventions he initiated that got survivors fully recovered. I take no prisoners in advancing stroke recovery and exposing naked emperors. 

What is Dr. Sacco's impact factor in getting survivors recovered?

Renowned neurologist Ralph L. Sacco remembered for leadership, advancements in stroke 

Ralph L. Sacco, MD, MS, professor and chair of the department of neurology at the University of Miami Miller School of Medicine, died on Jan. 17 from glioblastoma, according to a statement from the university.

“Dr. Ralph Sacco’s work helped to cement the Miller School’s reputation and enhance Miami’s world-class standing in stroke and cardiovascular and brain health,” Henri R. Ford, MD, MHA, dean and chief academic officer of the Miller School, said in the statement. “He was a gifted researcher, a committed teacher and mentor, and an irreplaceable friend who was part of the nucleus of our institution.”

A native of New Jersey, Sacco attended Boston University School of Medicine, where he assisted his mentor in the Framingham Heart Study, the country’s longest-running longitudinal analysis of risk for cardiovascular disease. Sacco later joined the faculty at Columbia University, where he founded the Northern Manhattan Stroke Study, an examination of underserved and understudied Black and Latino populations.

picture of male with glasses, white beard
Ralph Sacco

Sacco founded and served as executive director of the Florida Stroke Registry and founding principal investigator of the Florida-Puerto Rico Collaboration to Reduce Stroke Disparities and the Family Study of Stroke Risk and Carotid Atherosclerosis, according to the university statement.

In addition to chairing the department of neurology at the Miller School of Medicine, Sacco was the Olemberg Family Chair in Neurological Disorders, chief of neurology at Jackson Memorial Hospital and executive director of the Evelyn F. McKnight Brain Institute. He also directed and served as multi-principal investigator at the Miami Clinical and Translational Science Institute.

Sacco served as president of the American Academy of Neurology (AAN) from 2017 to 2019 and was the first neurologist to become president of the American Heart Association (AHA), a position he held from 2010 to 2011. Sacco was the only physician to be named head of both professional organizations.

A fellow of the Stroke and Epidemiology Councils of the AHA, the AAN and the American Neurological Association, Sacco also sat on the board of directors of the World Stroke Organization (WSO). He served as editor-in-chief of the AHA’s peer-reviewed scientific journal Stroke.

Sacco received numerous awards and distinctions throughout his career, notably the WSO’s Global Leadership Award and the AHA’s Gold Heart Award, Distinguished National Leadership Award and 2022 Distinguished Scientist Award. At its chair summit in December, the AAN announced the event would be renamed the Ralph L. Sacco Neurology Chair Summit, according to the university statement.

“Ralph was one of a kind,” AHA and American Stroke Association CEO Nancy Brown said in a joint statement from the groups. “His leadership was unparalleled, and his warm, generous heart and care transcended his research and clinic to every person fortunate to meet him and likely become a friend.

“The association is forever grateful that he chose to share his time and extraordinary talents with us, and we will continue to honor his memory through the work we do to champion health equity and brain health resulting in longer, healthier lives for all people.”

Reference:

Wednesday, January 6, 2021

Achievements and New Initiatives for Stroke in 2021

 Oh God; what ABSOLUTE FUCKING LAZINESS. Nothing on survivors or rehab or 100% recovery. WHY THE HELL IS STROKE IN YOUR NAME ANYWAY?

What is your impact factor in getting survivors recovered?

And Dr. Sacco was former president of the American Heart Association.

Achievements and New Initiatives for Stroke in 2021

Originally publishedhttps://doi.org/10.1161/STROKEAHA.120.033123Stroke. 2021;52:5–7

Although we started the year celebrating the 50th anniversary of Stroke, coronavirus disease 2019 (COVID-19) brought many new challenges that changed all of our lives. As we start a new year, we are all hoping that 2021 brings better times and a new normal. I am confident that more advanced treatments and vaccines for COVID-19 will become available, and enlightened leadership will help guide us toward better implementation of preventive measures. I also hope for improved initiatives to address racial inequality, improve equity, diversity and inclusion, and enhance health equity. We will also strive to advance the American Heart Association (AHA) mission to be champions for health equity and advance cardiovascular health for all, including identifying and removing barriers to health care access and quality.

See related article, p 8

As 2021 begins, I am happy to report on some notable achievements over the last few months. First, I want to thank the amazing editorial board and the over 1600 reviewers from 66 countries who help us maintain the high-quality of our publications. I am also very proud of the progress we have made in improving equity and diversity on our Stroke editorial masthead. We now include 294 people with 47% women (up from 29% in 2019), 43% international, 21% Asians, 5% Hispanic (up from 3%) and 5% Black participants (up from 1%). Without all of these hard-working and dedicated members of our editorial board, we would not be where we are today.

We have other plans to continue to be more inclusive and call upon more diverse individuals to author, review, and engage in the leadership of the journal. To achieve our goals, we will continue to support our trainee reviewer program to provide clinical and translational science trainees the opportunity to learn how to be a good reviewer, perform peer reviews, and receive some constructive feedback. We also plan to launch a new intensive Editor-in-Training program for a selected group of under-represented people in medicine. Our goal is to build a broader pipeline of future editorial board leaders by providing a mentored editorial experience with our associate editor team.

Other approaches to address inequity in our editorial process include the following: (1) collecting better demographic data in eJournal Press, our article submission system; (2) utilizing this information to enhance reviewer selection and increase use of under-represented racial and ethnic groups in peer review; (3) requesting that section editors include women and diverse authors when nominations are made soliciting invited content; and (4) encouraging all board members and senior editors to act as ambassadors at meetings to identify and recruit diverse individuals to the journal.

I also wanted to share some other good news. In July 2020, we were notified about a rise in our 2-year impact factor to 7.190 (from 6.046) and 5-year impact factor of 7.113 (from 6.572). We remain ranked No. 1 among stroke journals, No. 6 out of 65 for peripheral vascular disease journals, No. 16 out of 1204 clinical neurology journals, and No. 4 out the 12 AHA journals. Our new team cannot really claim any of the credit. The hard work of the many editorial members over the last few years need to be recognized and congratulated.

We also have ended the year with a record number of submissions to the journal on track to have over 4100 articles submitted to Stroke with a 18% increase in original article submissions and 33% increase in other types of articles over the last year. We received many reports about COVID-19 that we expedited in the early months of the pandemic and were collated by the AHA coronavirus resource site. Unfortunately, with the increased number of submissions, we are only able to publish 12% of original articles.

As many of you have heard by now, a new open-access journal, Stroke: Vascular and Interventional Neurology will be launched in July 2021. This will be a first in many ways since it is a joint collaboration and ownership between the AHA and the Society of Vascular and Interventional Neurology. While Stroke will continue to evaluate and publish interventional articles, we will also be able to refer many high-quality articles to this journal just as we currently do with other AHA journals such as Journal of the American Heart Association.

I am also happy to announce that for the first time one of our own, Hooman Kamel, a vascular neurologist at Cornell Weill Medical Center, has been named as one of the 2020 Joseph A. Vita award recipients for his contributions to cardiovascular health and to the AHA journals. Selections for this prestigious award are made by the AHA Scientific Publishing committee based on nominations from all journal editors.

With this January 2021 issue, we also are launching a few new initiatives. The Advances in Stroke articles will provide brief summaries of some hot topics and breaking news in specific disciplines authored by our section editors each month. Rather than try to cram these all into one issue, we are planning to provide specific Advances each month and summarize the prior calendar year. This month you can find Advances in Stroke for Treatments–Recovery and a new section on Digital Health.

Page limits are a limiting factor for the number of articles we can publish in-print or online each year. We have expanded our brief article type labeled Research Letters and encourage authors to use this opportunity to update others about advances in the field. These brief 750-word articles with only 1 figure and no abstract are very focused and meant to make an important innovative point in any topic areas covered by Stroke.

We are also making a major change in how we handle Letters to the Editor. As it turns out, our Letters take up a sizable number of pages and accounted for 182 ePages in 2020. The AHA journals have a new online process for remarks on published articles that has been working for Circulation and other journals that has now launched for Stroke. This system allows our readers to write letters about published articles, have them reviewed by our editorial board, and have our authors provide a response. All letters to the editor will track with the online contents of the article and allow us to print other articles with the saved pages. We still have a backlog of letters to the editor that will be appearing the old way, but I hope our readers will find this new system more efficient for following important scientific discussions about our published articles.

We live in a much more enlightened digital age and they say a picture paints a thousand words. We have had graphic abstracts for some time for our translational science articles and started encouraging them for our clinical and population science submissions. Starting in January, we are now asking all authors of our original research articles to create a visual abstract that we will feature online as a way to succinctly summarize the key points of the article. We promise to disseminate these more widely through social media to more effectively spread science to our readers. We also are enhancing our social media presence on Twitter, Facebook, Instagram and Reddit and have continued to expand our blogging editors. We are also planning to initiate Stroke Podcasts very soon.

We have increased the word limits for our review articles and engaged our increased number of section editors to solicit state of the art reviews across our many topic areas. We will continue to collect some multi-article reviews in our Focused Updates in Cerebrovascular Disease. In November, we were able to publish our Focused Update in Health Equity, and we have other great topics planned in 2021.

We have also increased the number of solicited editorials to comment on our publications and place them in perspective. Moreover, we are changing the format of our Table of Contents in-print and online to mirror that of Circulation and some other AHA journals. You will now find the editorial will be placed just after the published article to allow the reader to quickly evaluate the source article and the perspectives of the editorial authors.

Other strategic goals include an increase in the number of timely simultaneous publications with our scientific meetings, attracting more publications of clinical trial results, and continuing to be dedicated to training early career professionals. To advance the next generation of editorial board members, we are maintaining our trainee assistant reviewer program. We also have expanded the number of our trainees and fellows engaged as bloggers to help spread the word about articles and trending topics in our field. We will continue to solicit special articles for our International Stroke Early Career and Training section.

All in all, we continue to do everything we can to advance the Stroke mission and achieve our vision. Our mission is to drive innovative interdisciplinary research, transform patient care, and enhance our understanding of disorders of the cerebral circulation and our vision is to be an indispensable, inspiring, and trusted source of high-quality scientific knowledge for all stroke disciplines. Thanks for all of your help throughout a challenging 2020, and we look forward to success and progress in 2021.

Footnotes

The opinions expressed in this article are not necessarily those of the American Heart Association.

For Disclosures, see page 7.

Correspondence to: Ralph L. Sacco, MD, Departments of Neurology and Public Health Sciences, Miami Clinical Translational Science Institute, Evelyn McKnight Brain Institute, Miller School of Medicine, University of Miami, 1120 NW 14th St, Suite 1352, Miami, FL 33136. Email
 

Friday, February 23, 2018

Novel Stent Retriever Is Quick to Restore Flow

Once again the wrong endpoint is used. The endpoint is 100% recovery, NOT the lazy 50% flow restored. If Dr. Sacco being president of the ASA at one time produced anything useful for survivors it is not commonly known.

Novel Stent Retriever Is Quick to Restore Flow

  • by Senior Associate Editor, MedPage Today
  • This article is a collaboration between MedPage Today® and:
LOS ANGELES -- A novel stent retriever device achieved high rates of rapid, substantial reperfusion for large vessel ischemic strokes without significant safety concerns, the pivotal ARISE II study showed.
With the EmboTrap device, 80% of recipients reached the primary endpoint of more than 50% flow restored (modified TICI 2b, 2c, or 3 flow) within three passes without aspiration or other rescue therapy, including 65% with near-complete or full flow.
Notably, 51.5% of those treated had this substantial flow restored on the first pass, Osama Zaidat, MD, of St. Vincent Mercy Hospital in Toledo, Ohio, reported here at the International Stroke Conference.
While the final rate of mTICI 2b-3 flow was 93%, on par with other mechanical thrombectomy trials, Zaidat noted that the high early-pass revascularization rate was a "remarkable" advance.
"That's what the trial is, it's pushing the limit," he said at a press conference. "The physicians are taking the right patients and they are taking them fast. And I think that's why I think we achieved one of the highest mRS 0-2 at 67%" compared with other studies.
The proportion of participants with a good functional outcome (modified Rankin Scale score 0-2) was 67.3% at 90 days.
J Mocco, MD, of Mount Sinai Hospital in New York City, who presented another trial at the same session reporting mRS 0-2 achieved in 52% of patients treated with an aspiration-first approach and 49% with a stentriever-first strategy, agreed that this is an important evolving area.
"Sooner and fewer is always better," he told MedPage Today at the press briefing, "although I think that more important right now is to focus on the time component to getting at least TICI 2b or greater. If you can do that with one pass, obviously that will be faster. If it's two passes and it's still very quick, that's just as important. We need to focus on the quality of reperfusion ... we need to move our conversation to 2c and 3, we need to be talking about 90% of the brain getting blood flow or more, not 52%."
"For one pass efficacy, that is something that seems to be clear but does not have clear proof," he added. "However, for achieving 2c or 3 versus TICI 2b, has overwhelming proof" of impact on clinical outcomes.
"The first pass is a nuance, I think," agreed Ralph Sacco, MD, of the University of Miami, and president of the American Academy of Neurology. "It may be a predictor of how fast you can then subsequently open up the vessel, I think that's the data they need to show."(I call that lazy, wrong data to show)
The trial included 227 patients treated with the EmboTrap device for large vessel occlusions within 8 hours of last time known well before onset of symptoms. Median time from onset to puncture was 214 minutes; median time from puncture to revascularization was 35 minutes.
The primary safety endpoint of symptomatic intracranial hemorrhage within 24 hours of treatment or other serious adverse events occurred in 5.3%. No patients died related to the procedure in the first week, although 9.0% died from any cause by day 90.
Device developer Cerenovus has applied for FDA clearance of EmboTrap based on ARISE II.
ARISE II was sponsored by Neuravi (since acquired by Cerenovus, a Johnson & Johnson company).
Zaidat disclosed being a consultant for the company.

Friday, August 5, 2016

Are Stroke Centers Life Savers? Study finds small advantage, but only if you get there quickly

If Dr. Sacco being president of the ASA at one time produced anything useful for survivors it is not commonly known.
https://medlineplus.gov/news/fullstory_160087.html
The odds of surviving a stroke are slightly better for patients treated at hospitals with a specialized stroke department, known as primary stroke centers, a new study finds.
But that benefit was only seen if stroke patients got to a stroke center in less than 90 minutes, the study authors said.
"Treatment of stroke is very time sensitive. As the saying goes, time is brain," said lead researcher Dr. Kimon Bekelis.
"So the faster you intervene, the faster the patient recovers," he said.
Bekelis is an instructor at the Dartmouth Institute for Health Policy and Clinical Practice at Dartmouth-Hitchcock Medical Center in Lebanon, N.H.
Primary stroke centers provide integrated care, including timely administration of medications, such as the clot-busting drug tPA (tissue plasminogen activator, also known as alteplase). They also offer special procedures to reduce the effects of a stroke, Bekelis said.
Many of these treatments are only available at stroke centers or are delivered faster there, which may account for the difference in survival, compared with treatment at a community hospital, he said.
Most Americans live within 90 minutes of a stroke center, but in rural areas the travel time can be longer, Bekelis said. He suggested that to fill this gap, speeding travel time using helicopters might be one way of improving survival.
Dr. Ralph Sacco is chairman of neurology at the University of Miami Miller School of Medicine. He said, "This analysis provides further evidence of the importance of being treated for stroke at a certified primary stroke center, even if it takes up to 90 minutes to get there."
The study only looked at differences in death rates for stroke centers compared to standard hospitals. But, it's likely there are other potential benefits -- such as reduced disability -- for patients treated in certified stroke centers, Sacco suggested.
"Longer delays in getting to a stroke center might lead to decreases in the utilization of acute stroke treatments," he explained.
"We need to consider other approaches, such as the use of telestroke [which puts doctors who are treating a stroke patient in direct contact with a stroke specialist using technology], and increasing the number of stroke-ready hospitals to increase the access of patients to timely stroke care," Sacco said.
For the study, the researchers collected data on nearly 866,000 Medicare patients, average age 79. All had a stroke between 2010 and 2013.
Almost 54 percent of these patients were treated at a stroke center. There are 976 stroke centers in the United States, the report noted.
Twenty-four percent of those in the study lived closer to a stroke center than to another hospital, the investigators found.
The study showed that patients who can get to a stroke center within 90 minutes had a nearly 2 percent higher chance of surviving a stroke after seven and 30 days, compared with patients treated at hospitals without such centers.
Bekelis and his colleagues also found that patients treated at a stroke center were twice as likely to receive tPA -- 6 percent versus nearly 3 percent -- than people treated at a standard hospital.
The report was published online July 25 in JAMA Internal Medicine.
At least one stroke expert expressed concern about sending patients who may not have had a stroke to stroke centers, potentially overwhelming the system.
"It is important to balance the benefit you get by going directly to a stroke center against whether that patient is actually having a stroke, or having a stroke that could be treated as effectively in a community hospital," said Dr. Lee Schwamm. He's vice chairman of the department of neurology at Massachusetts General Hospital in Boston.
It can be difficult to diagnose a stroke in the field, said Schwamm, who wrote an accompanying editorial in the journal. (Well then you solve for having fast, accurate cheap and objective diagnosis in the ambulance. Don't just fucking explain why you can't do it today, explain how you will do it in the future.)
"We need an understanding of how to improve pre-hospital diagnosis so that EMTs [emergency medical technicians] have the guidance they need to make the right choice," he said. "This might include telephone conferencing with a stroke specialist or a smartphone app." (No, you eliminate the need for a neurology specialist.)
SOURCES: Kimon Bekelis, M.D., instructor, Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth-Hitchcock Medical Center, Lebanon, N.H.; Lee Schwamm, M.D., vice chairman, department of neurology, Massachusetts General Hospital, Boston; Ralph Sacco, M.D., chairman of neurology, Miller School of Medicine, University of Miami; July 25, 2016, JAMA Internal Medicine, online

Sunday, November 17, 2013

‘Sci-fi’ system aids stroke victims

Sounds fascinating but will it work for those like me whose motor cortex is mostly dead? In other words can it work on the upstream brains areas. ie. Will it be able to read the pre-motor cortex signals? In my case that is mostly dead also. Then will it be able to read the executive control signals instead? Simple questions to be answered.
These people are still going down the wrong route where the assumption is that we just need to improve therapy to make survivors better.
Wrong, wrong, wrong, You need to stop the neuronal cascade of death resulting in less dead and damaged neurons 
http://www.thisisguernsey.com/news/uk-news/2013/11/17/sci-fi-system-aids-stroke-victims/
Giving paralysed stroke patients a set of thought-controlled virtual reality hands could help them regain movement of their limbs, scientists believe.
The sci-fi approach was developed to improve the rehabilitation of stroke victims by getting them to reactivate damaged regions of their brains.
Six patients watched a 3D video of arms and hands, creating the illusion that they were their own. Signals sent to a computer via electrodes attached to the head allowed the patients to move the limbs simply by using their imagination.
In as little as three two-hour sessions, the patients learned how to reach out to a glass of water with 81% accuracy.
The system is designed to help patients rehabilitate themselves, rather than relying on a therapist physically manipulating their limbs.
“Using a brain-computer interface, we’ve created an environment where people who may be too physically impaired to move can practice mental imagery to help regain use of their arms and hands,” said Alexander Doud, from the University of Minnesota, US, who led the study.
“During rehabilitation, usually a therapist will move the patient’s hand or arm in the desired direction while asking that patient to imagine they are making the movement. In this practice space, the patients can control photorealistic hands by thinking about using their own hands without actually moving at all.”
” The system is created in a way that could allow it to be used to practice a wide variety of desired activities, such as picking up a toothbrush or opening a jar, with very little additional work to set up the system,” Mr Doud added. “This can make it even more patient specific and that leads to patient motivation.”
The findings, presented at the American Heart Association’s Scientific Sessions meeting in Texas, prove the feasibility of a new approach that could become an affordable rehabilitation tool, he said. However he stressed that the research still had to be replicated in a larger, more diverse population of patients.
“This is an engaging system that encourages patients to practice using the areas of their brain that may have been damaged or weakened by their stroke, and the technology could be used along with commonly provided rehabilitation therapy for stroke,” said Mr Doud.
Rehabilitation therapy using physical movements and mental imagery has been known to help patients overcome paralysis even years after suffering a stroke.
Professor Ralph Sacco, from the University of Miami, former president of the American Heart Association, said: ” Although this study may be about the future, we know now that physical therapy can improve outcomes after stroke.” (barely)

Wednesday, November 6, 2013

"prisoners of the past" and "pioneers of the future." - Stroke

This comes from Newt Gingrichs' new book "Breakout,".
the divide between those who think the party needs no new ideas, no positive message, and no fundamental change on the one hand, and those who want to be aggressive about breaking out to a better future on the other.
I'll apply it to the stroke world.
Most of the stroke world is still enamored of tPA and the F.A.S.T. campaign.
tPA was approved in 1996 and has an appalling 12% efficacy.
F.A.S.T.  assumes that getting to the hospital fast will save the brain. This is an incorrect assumption due to tPA failures and no protocol to stop the neuronal cascade of death.  The pushers of F.A.S.T., all the stroke associations, are rooted in the past and can't get rid of the blinders they have put on themselves. No new ideas.
ASA - Dr. Sacco,
NSA - Mr. Baranski, 

WSO - Dr. Stephen Davis
are all prisoners of the past, none have reached out to stroke survivors and are just working on tweaking the status quo.
I don't see how the boards of directors can justify such failure of leadership.
The WSO has come up with the pathetic 2010 Stroke: working toward a prioritized world agenda
The status quo will not be enough for the coming tsunami of stroke.
 

Wednesday, July 24, 2013

Is anyone listening for stroke?


Having published almost 4000 blog entries on stroke, considering the number of views I've had, and my  naming leaders of stroke groups. I'm amazed that I have not been contacted by any stroke group, medical stroke doctor or stroke researcher. But then I'm a stupid non-medical stroke survivor not worth listening to. I'm terribly stroke-addled to the normals.
 Do they all really think they are doing the best job they can?
They're not, they are all failing by any study of results.
ASA - Dr. Sacco, 

NSA - Mr. Baranski, 

WSO - Dr. Stephen Davis

I guarantee that after they have a stroke and find out the reality of lack of results they might have the 'come to Jesus moment'. Do you want to wait that long? Or be proactive and demand results now.
This was written because I saw the book Magnificent Mistakes in Mathematics / by Alfred S. Posamentier and Ingmar Lehmann.
Time is Brain, you know. F.A.S.T.  How many neurons will they let die because of inaction?
 

Wednesday, May 1, 2013

Stroke awareness month - May

Big Whoopee. We'll get tons of reminders about F.A.S.T., prevention ideas and other feel good items from the presenters. It may make them feel useful but if they really wanted to be helpful they would support a Great stroke association (it doesn't yet exist) that would actually do hands on work to prevent neuronal death. Telling me that the Mediterranean diet reduces my stroke risk by x% may make you feel better but does very little good in the grand scheme of stroke. Instead, creating a national stroke plan similar to the national alzheimers plan would be a much better use of time. Whomever created this is just like a politician, make it look like something is being accomplished without actually doing anything useful.
Dr. Sacco, Mr. Baranski your reply? Will you actually work on neuronal death?

Wednesday, January 23, 2013

Every 40 Seconds a Stroke Occurs in the United States

Once again the ASA shows the only thing it is good for, putting out press releases and dumping responsibility for diagnosing stroke onto the patient/bystanders.  With a multitude of hyperacute therapies stopping the neuronal cascade of death, the disability from stroke could be vastly reduced.
Dr. Sacco, Why don't you work on that?  A Great stroke association would.
http://www.digitaljournal.com/pr/1029310