Perfusion I: Introduction and
Dynamic Susceptibility Contrast (DSC) Imaging
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Perfusion Imaging Part I Questions
- How is perfusion defined and measured?
- How are parameters like BF, BV, and MTT defined and used in perfusion imaging?
- What are the differences between DSC, DCE and ASL perfusion methods used in MRI?
- How do you perform a DSC perfusion study?
- If gadolinium contrast is used to increase signal intensity on routine MR images, why does it decrease signal on DSC perfusion images?
- What about areas of contrast enhancement? Surely some T1 effects of gadolinium are present there...
- Why doesn't the DSC curve return to its baseline after passage of the contrast bolus?
- What is the negative enhancement integral and how is it calculated?
- Is it possible to quantify the actual concentration of Gd from its signal in a DSC study?
- What is the arterial input function (AIF) and why do you need to measure it?
- How is the arterial input function used to extract more quantitative flow information from the DSC data?
Perfusion Imaging Part I Topics