Gadolinium and ASL
Can gadolinium be given in conjunction with ASL?
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Gadolinium can be given with ASL. Just don't expect to see any blood flow!
Gadolinium shortens the T1 of blood significantly so that nearly complete recovery of its longitudinal magnetization occurs between the time of inversion and readout. The tagged and control images are nearly identical and no flow information is revealed when subtracted. Generally waiting at least 8-12 hours after gadolinium administration is recommended in patients with normal renal function before repeat ASL imaging is performed. For accurate quantitative measurements at least 24-48 hours may be needed. |
ASL image post gadolinium
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References
Diebler AR, Pollock JM, Kraft RA, et al. Arterial spin-labeling in routine clinical practice, Part 1: techniques and artifacts. AJNR Am J Neuroradiol 2008; 29:1228-1234.
Diebler AR, Pollock JM, Kraft RA, et al. Arterial spin-labeling in routine clinical practice, Part 1: techniques and artifacts. AJNR Am J Neuroradiol 2008; 29:1228-1234.
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