Frances was born in Italy, the youngest of thirteen children. Her parents sent her to school in a convent boarding school.
Having finished school, she tried to become a sister. But the convent wouldn't accept her because of her poor health. She tried again at another convent, but they turned her down too.
When a priest asked her to teach in a school for girls, she agreed and continued teaching for six years. Then a bishop asked her to start a missionary order of sisters to care for poor children in hospitals and schools. The order was called the Sacred Heart of Jesus.
The Pope asked her to travel to the United States and work among the Italians living there. She became an American and started many orphanages, schools and hospitals.