The Limits of Memory
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by James Wallace Harris, 3/3/25 It annoys me more and more that I can’t
recall names and nouns. I don’t worry yet that it’s dementia because most
of my fri...
1 week ago
Well, all this is interesting to me, anyway, and that's what matters here. The Internet is a terrible thing for someone like me, who finds almost everything interesting.
When a slave-owner strikes a male or female slave with a rod and the slave dies immediately, the owner shall be punished. But if the slave survives for a day or two, there is no punishment; for the slave is the owner’s property.
As for the male and female slaves whom you may have, it is from the nations around you that you may acquire male and female slaves. You may also acquire them from among the aliens residing with you, and from their families that are with you, who have been born in your land; and they may be your property. You may keep them as a possession for your children after you, for them to inherit as property. These you may treat as slaves, but as for your fellow Israelites, no one shall rule over the other with harshness.
Cancer is not a creative, original disease; it has not been honed by ages of evolution to craft novel lines of attack on your body. Instead, it’s an opportunistic thief. Cancer misuses and perverts existing processes in your cells to send them out of control. Everything cancer does is simply the same thing your cells normally do, only amplified and unconstrained, driven by damage to the genes that would normally regulate their behavior.
Here’s a metaphor, a car with a dangerous defect. It has acquired a glitch in the accelerator so that every time you start it up, it immediately roars up to full speed, as if you’d floored the pedal. The problem hasn’t created anything new in the car, it’s just taken something you normally need to do, that is, regulate the speed of the machine, and stripped you of all ability to control it. That’s what an oncogene does; it is a gene that is normally involved in controlling the rate of cell proliferation, for instance, and a mutation has broken it in such a way that it now tells the cell to divide as rapidly as possible.
Now if you were driving down the freeway and suddenly your accelerator were stuck and you couldn’t slow it down, you’d have alternative strategies to stop (and so does the cell). You could hit the brakes or shift gears or turn off the ignition key. Cancers acquire another set of mutations that destroy the ability to shut off cell processes, analogous to breaking the brake pedal or snapping off the gear shift handle. These genes that can block the effects of out-of-control cell regulators are called tumor suppressors, and I’ll write about those at another time. Today I focus on oncogenes, regulators of the cell that must be damaged by mutation to produce an excessive response.
The first concern that comes to everyone’s mind is that you don’t want to have your cells running amuck — no one wants cancer. Just as you can do your best to maintain your car, you can also live sensibly — eat in moderation, avoid carcinogens or other behaviors that expose you to radiation, and get regular checkups — to reduce the likelihood of deleterious mutations. But they can happen anyway, through no fault of your own. Every time your cells divide, there is a very small chance of an error in replication that inserts a mutation into an oncogene. Just existing, even while doing everything exactly right to maximize your health, brings with it a base chance for a mutation. Given normal rates of cell division, every single one of you reading this is going to acquire about 20,000 DNA lesions today and every day. Almost every one of them will be patched up by DNA repair mechanisms (you have no idea how important DNA repair is to your continued health), but even so, one will occasionally slip through — over your lifetime, your cells will acquire an estimated 10,000 mutations. Live long enough, playing these odds, and cancer is essentially inevitable.
So cancer is fundamentally a chance process. There is no reason people get cancer, no purpose behind it, and everyone is susceptible. Some behaviors can increase the odds — smoking, failing to use sunblock — and you can also inherit genetic predispositions that increase the likelihood of acquiring a full set of mutations that lead to cancer, but ultimately, no one is at fault for cancer.
A major evangelistic ministry is preparing to launch a 30-minute documentary that Christian leaders say will offer a “devastating,” “lights out” challenge to the evolutionary worldview. ...
The main premise behind “Evolution vs. God” is that top evolutionary scientists cannot convincingly support their theory, and instead rely heavily on unfounded assumptions. Even when Comfort personally interviews influential evolutionists from major universities in the film (such as well-known atheist PZ Myers), they are unable to satisfyingly answer Comfort’s prodding questions.
“As you will see on “Evolution vs. God,”” Comfort stated, “not one of the experts could give me a whisper of evidence for Darwinian evolution. The movie is going to shatter the faith of the average believer in evolution, and strengthen the faith of every Christian.”
I was one of those scientists. NO, I did not disagree with Dawkins about evolution or the evidence for evolution; NO, nothing I said provided any support to creationist claims; NO, there is not a lack of evidence for evolution.
What actually happened is that I briefly discussed the evidence for evolution — genetics and molecular biology of fish, transitional fossils, known phylogenies relating extant groups, and experimental work done on bacterial evolution in the lab, and Ray Comfort simply denied it all — the bacteria were still bacteria, the fish were still fish. I suspect the other scientists did likewise: we provided the evidence, Ray Comfort simply closed his eyes and denied it all.
Now we were getting to the heart of the matter; anecdote trumps evidence. I tried to be polite and diplomatic: "It seems like you don't really want the cases investigated, and certainly not solved. See, that's what I do: I investigate mysteries to solve them. If I'm going to spend time and effort on a case, maybe days or weeks or months, I'm going to do my best to understand and explain the mystery. It's kind of the opposite of what you want, so I don't really think I can help you. If you just want to get people who saw UFOs or ghosts or Bigfoot on camera telling their stories, you don't need me for that."
She seemed slightly taken aback: "But you're a respected paranormal investigator, you came recommended, and have credentials... I thought you'd be a good fit?" ...
I finally realized that what they really were looking for was an incompetent "investigator," someone who would appear on their show and pretend to use science in investigations-someone who would superficially appear smart and entertaining but who in the end would be baffled and stumped by the mysteries they faced.
I was perfectly willing to admit if I was stumped or couldn't fully explain a case, but I was not willing to pretend to be stupid or incompetent: "I see... If I can't solve a case, or if there are real unanswered questions about it, I don't mind admitting that I don't have all the answers. But I'll give it my best shot-I'm not going to pretend I don't have a clue if I have a pretty good idea of the explanation."
Producer: "Okay, I understand," she said, though I don't really think she did. "Well, do you know anyone who might be interested?"
Remember the Scopes Monkey trial? You know, that case from way back in the '20s where a school teacher was convicted of teaching evil monkey evolution science to the good Christian children of Tennessee?
Tennessee sure hasn't forgotten…
Tennessee Gov. Bill Haslam (R) announced yesterday that he will "probably" sign a bill that attacks the teaching of "biological evolution, the chemical origins of life, global warming, and human cloning" by giving broad new legal immunities to teachers who question evolution and other widely accepted scientific theories…
Although the bill is written to seem benign, as it neither specifically authorizes the teaching of creationism nor permits teachers to do more than criticize scientific theories "in an objective matter," the practical impact of this bill will be to intimidate all but the heartiest of school administrators against disciplining teachers who preach the most outlandish junk science in their classrooms.
Democrats like to make fun of the GOP candidates for being stuck in the '50s, but at least they're in the post-WWII era. Tennessee is currently reliving the '20s, but without all those fun speakeasies and flapper dresses.
Between this "monkey" law and the state's "Don't Say Gay" bill, the state is really not doing itself any favors. Ironically, although the "theory" of evolution is pretty much a scientific fact at this point,* the people of Tennessee are themselves pretty strong evidence against evolution.
In evolution, as in life, some things are easier than others. It seems to be pretty straightforward to evolve complex eyes, which have turned up dozens of times.
Similarly, for some groups of animals it's easy to stop laying eggs and start giving birth to live young. Backboned animals have evolved live birth no fewer than 132 times, and nowadays a fifth of lizards and snakes give birth. Human mothers may disagree, but live birth is clearly not that difficult.
What is difficult, however, is nourishing unborn young the way mammals do. A female mammal allows each embryo to burrow deep into the wall of her womb, where it takes nutrients straight from her blood. This intimate arrangement was long thought to have only evolved once, in mammals.
Not so. It now appears that it evolved at least twice: once in mammals, and once in an obscure African lizard called Trachylepis ivensii. ...
All live-bearing reptiles have a basic placenta, but unlike its mammalian counterpart the embryo doesn't get much food that way. It can't: although it nestles up against the oviduct wall, the embryo remains inside a remnant of eggshell that acts as a barrier. Instead, it is nourished by a large yolk.
A very few reptiles, including T. ivensii, break this rule. Their eggs are small, with little yolk, so they must get lots of food from their mothers via the placenta. But only T. ivensii allows the embryo to implant itself in the oviduct wall. "It's unprecedented," Blackburn says. ...
But the arrangement has its problems, Blackburn says. An embryo in close contact with its mother's blood risks being attacked by her immune system. Male embryos could also be "feminised" by her sex hormones. That might explain why full-scale placental feeding has evolved so rarely.
The only reptiles that come close to T. ivensii belong to a South American skink called Mabuya. Their placentas are complex and transfer plenty of nutrients, and there is some evidence of embryonic cells being able to invade the oviduct wall in a limited way. Another African species, Eumecia anchietae, also feeds its young entirely through its placenta.
Neither shows as much intimacy as T. ivensii, however, and Blackburn also says their placentas are "fundamentally different". That may mean placental feeding has evolved in skinks not once, but three times. Clearly, in evolutionary terms these reptiles have the knack.
The first speaker up was an 82 year old woman who they introduced as being up there because they realized they needed a woman speaker. She began her speech by telling us that she had no credentials and her speech was basically taken from some book. I can’t really tell you what her speech was about as they had the microphone too far from her and her mispronunciation of words became incredibly distracting. What I did gather was that the Creation Evidence Expo will help you become a “free thinker” and that you can’t have sex with other species and produce offspring.
Don says: This woman was truly baffling herself with bullshit. As Louise said, she admitted that her speech was drawn almost exclusively from some guy's book and boy did it show. She very clearly did not know the meanings of the words she was using. Large swaths of her speech were dedicated to homology and Jack Chick-style strawmen thereof ("Ignorant, evil evolutionist teachers use circular reasoning to prove homology!"), a concept with which I do not believe for a damn second she was remotely familiar. Especially since she consistently pronounced the word "homologous" as "homolojuss." She talked a lot about DNA using words that only few laypeople understand and appreciate and she, given her flat delivery (she was reading from some dude's book, remember) was not among that number. She said that being creationists made people "critical thinkers" against the "dogma" and "orthodoxy" of "Darwinism." This is an excellent example of how good the religious right is at coopting the language of the opposition and using it against them.
She talked about lifeways and world systems and oppression and freeing one's mind and overall reminded me a little bit of an idiot creationist version of bell hooks.After she was finished the MC praised her as "Just a mother, not a scientist" who only wanted the best for our kids. Apparently being a mother confers intellectual authority over vaccinations and the origins and development of life.
In between speakers a choir sang for us. The good news is they had a nice sound; the bad news is they only knew one song and sang it twice in a row. Turns out the choir and their parents accounted for about half of the audience. After they sang they all left.
According to the Bible (Genesis 2:7), this is how humanity began: "The Lord God formed man of the dust of the ground, and breathed into his nostrils the breath of life; and man became a living soul." God then called the man Adam, and later created Eve from Adam's rib. [*]
Polls by Gallup and the Pew Research Center find that four out of 10 Americans believe this account. It's a central tenet for much of conservative Christianity, from evangelicals to confessional churches such as the Christian Reformed Church.
But now some conservative scholars are saying publicly that they can no longer believe the Genesis account. Asked how likely it is that we all descended from Adam and Eve, Dennis Venema, a biologist at Trinity Western University, replies: "That would be against all the genomic evidence that we've assembled over the last 20 years, so not likely at all."
>it is unlikely that we all descended from a single pair of humans.
I thought that Lucy/African Eve was the one that we're all descended from. Or was that a single pair of humans... Lucy and multiple males.
"Here your mom was asking about evolution, and you know it's a theory that's out there, and it's got some gaps in it. In Texas we teach both creationism and evolution in our public schools," Perry said. "Because I figure you're smart enough to figure out which one is right."
The Intelligent Design creationists have been having a secret meeting in Italy, where they claim to be challenging Darwinian orthodoxies. Well, semi-secret: they brought in David Berlinski's daughter to pretend to be a "journalist" and throw gentle little softballs in youtube interviews, but many of the attendees are anonymous, the meeting program is not available, and the place is stocked with devotees of religious orthodoxy who are singularly clueless about science. What it really is is a great big creationist circle jerk where everyone is free to say stupid things and not have one of those annoying evidence-based scientists in the audience asking difficult questions, and also avoid real journalists who might publicly expose their inanity. ...
Yes, their careers are in danger, because disciplines that value rigor and evidence and science are not going to be impressed at all by deluded cowards who hide in closets and whisper oft-debunked stupidities at one another. If you've got the goods, stand and deliver; show us your evidence, explain your reasoning, persuade people who disagree with you with the strength of your argument. They can't, so they scurry off to picturesque villas in Tuscany, shoo away those difficult criticisms, and sit and reassure each other that they are very clever indeed while mangling information theory and biology.
My favorite quote from Darwin's Origin is so appropriate here.
It is so easy to hide our ignorance under such expressions as the "plan of creation" or "unity of design," &c., and to think that we give an explanation when we only restate a fact. Any one whose disposition leads him to attach more weight to unexplained difficulties than to the explanation of a certain number of facts will certainly reject the theory. A few naturalists, endowed with much flexibility of mind, and who have already begun to doubt the immutability of species, may be influenced by this volume; but I look with confidence to the future, to young and rising naturalists, who will be able to view both sides of the question with impartiality. Whoever is led to believe that species are mutable will do good service by conscientiously expressing his conviction; for thus only can the load of prejudice by which this subject is overwhelmed be removed.
There was an orthodoxy in Darwin's time, too, and it was the dogma of creationism. Darwin's advice to young scientists was to conscientiously express their convictions, and to get out and publish, publish, publish their observations. That's how science progresses, by wrestling with disagreement and confronting it with evidence and experiment.
Back when hardware meant bony plates and flesh-rending teeth, a living version of the humble screw evolved naturally in, of all places, the leg joints of weevils.
The legs of at least 15 kinds of weevils have tapering, threaded, somewhat pointed ends where their legs meet their bodies. As the leg shifts position, the threaded tip tightens or loosens along a ridge on the inside of a rounded hollow structure, researchers in Germany report in the July 1 Science. “This is the first description of a true screw and nut in an organism,”...