Assassin's Creed 2 Walkthrough

Talk to Mario and he'll send you on your final mission, to assassinate Rodrigo Boriga in the Vatican in Rome. The mission is more linear than any other you've done up to this point, and it requires much stealthiness. But at first, it requires you break into the Vatican. Climb the wall to the west and use the beams sticking out from the wall to jump to a hanging platform to the south.

From the platform, you can jump north onto the wall of the compound and make a straight-forward climb to the top. But beware, as there are guards waiting at the top of the tower. You can stealth assassinate one of them from the far side of the wall, but you'll get their attention with that attack. Quickly hop over the wall and fight the guards.

With the guards dead, locate a lever on the northern wall and pull it to open a gate to the next area. There are two guards at the far end of the next yard. If you're quick, you can run across the yard and execute a double assassination while they try to figure out what you're doing. The gate ahead is closed, but you can climb to a level above (on the right) to find a lever that opens the gate. Just watch out for the lone guard up top.

You'll have to fight a host of guards in the next area, so be ready for a brawl. You can get the jump on a couple with a double assassination. When the guards are killed, climb to the top of a tower to the west to hit the glowing waypoint. A cut scene leaves Ezio on a horse.

Very early in your horse ride, you'll likely get knocked off the steed by enemy guards ahead. After getting knocked off, you can stand and fight or simply hop back on the horse and take off again. There's a large jump you've got to hit at full gallop to get over. Once over, expect to get knocked off the horse again. This time, you'll want to kill the attackers.