| AFC Offense | ||
| Pos. | Name | Team |
| WR | Randy Moss* | New England |
| WR | Reggie Wayne* | Indianapolis |
| WR | Braylon Edwards | Cleveland |
| WR | T.J. Houshmandzadeh | Cincinnati |
| OT | Matt Light* | New England |
| OT | Jason Peters* | Buffalo |
| OT | Jonathan Ogden | Baltimore |
| OG | Alan Faneca* | Pittsburgh |
| OG | Logan Mankins* | New England |
| OG | Kris Dielman | San Diego |
| C | Jeff Saturday* | Indianapolis |
| C | Dan Koppen | New England |
| TE | Antonio Gates* | San Diego |
| TE | Tony Gonzalez | Kansas City |
| QB | Tom Brady* | New England |
| QB | Peyton Manning | Indianapolis |
| QB | Ben Roethlisberger | Pittsburgh |
| RB | LaDainian Tomlinson* | San Diego |
| RB | Joseph Addai | Indianapolis |
| RB | Willie Parker | Pittsburgh |
| FB | Lorenzo Neal* | San Diego |
| AFC Defense | ||
| Pos. | Name | Team |
| DE | Jared Allen* | Kansas City |
| DE | Kyle Vanden Bosch* | Tennessee |
| DE | Jason Taylor | Miami |
| DT | Albert Haynesworth* | Tennessee |
| DT | Vince Wilfork* | New England |
| DT | Jamal Williams | San Diego |
| OLB | James Harrison* | Pittsburgh |
| OLB | Mike Vrabel* | New England |
| OLB | Shawne Merriman | San Diego |
| ILB | DeMeco Ryans* | Houston |
| ILB | Ray Lewis | Baltimore |
| CB | Champ Bailey* | Denver |
| CB | Asante Samuel* | New England |
| CB | Antonio Cromartie | San Diego |
| FS | Ed Reed* | Baltimore |
| SS | Bob Sanders* | Indianapolis |
| SS | Troy Polamalu | Pittsburgh |
| AFC Special Teams | ||
| Pos. | Name | Team |
| Punter | Shane Lechler | Oakland |
| Kicker | Rob Bironas | Tennessee |
| Kick returner | Josh Cribbs | Cleveland |
| Special Teamer | Kassim Osgood | San Diego |
* = Starter
