SARS-CoV-2 (Q82069695)

On the origin and continuing evolution of SARS-CoV-2

0 references

0 references

0 references

0 references

SARS-CoV-2 without background.png
1,958 × 1,966; 3.59 MB

0 references

Coronavirus. SARS-CoV-2.png
2,048 × 2,048; 4.54 MB

media legend

Scientifically accurate atomic model of coronavirus (SARS-CoV-2). Each "ball" is an atom. Color legend: сobalt — membrana; turquoise — spike glycoprotein (S); crimson — E protein; pink — M protein; green — Hemagglutinin-esterases (HE); orange — glucose. (English)

0 references

Novel Coronavirus SARS-CoV-2.jpg
3,060 × 2,390; 2.38 MB

0 references

video

Endocytosis 7.webm
12 s, 1,920 × 1,080; 22.89 MB

0 references

official name

severe acute respiratory syndrome coronavirus 2 (English)

named by

International Committee on Taxonomy of Viruses

start time

11 February 2020

nickname

Wuhan's flu (English)

1 reference

https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/naming-the-coronavirus-disease-(covid-2019)-and-the-virus-that-causes-it

31 May 2021

coronavirus 2 du syndrome respiratoire aigu sévère (French)

1 reference

https://www.who.int/fr/emergencies/diseases/novel-coronavirus-2019/technical-guidance/naming-the-coronavirus-disease-(covid-2019)-and-the-virus-that-causes-it

9 November 2021

French

فيروس كورونا المسبب للمتلازمة التنفسية الحادة الوخيمة (Arabic)

1 reference

https://www.who.int/ar/emergencies/diseases/novel-coronavirus-2019/technical-guidance/naming-the-coronavirus-disease-(covid-2019)-and-the-virus-that-causes-it

9 November 2021

Arabic

严重急性呼吸综合征冠状病毒2 (Simplified Chinese)

1 reference

https://www.who.int/zh/emergencies/diseases/novel-coronavirus-2019/technical-guidance/naming-the-coronavirus-disease-(covid-2019)-and-the-virus-that-causes-it

9 November 2021

coronavirus de tipo 2 causante del síndrome respiratorio agudo severo (Spanish)

1 reference

https://www.who.int/es/emergencies/diseases/novel-coronavirus-2019/technical-guidance/naming-the-coronavirus-disease-(covid-2019)-and-the-virus-that-causes-it

9 November 2021

коронавирус тяжелого острого респираторного синдрома‑2 (Russian)

1 reference

https://www.who.int/ru/emergencies/diseases/novel-coronavirus-2019/technical-guidance/naming-the-coronavirus-disease-(covid-2019)-and-the-virus-that-causes-it

International Committee on Taxonomy of Viruses

9 November 2021

short name

SARS-CoV-2 (English)

named by

start time

11 February 2020

1 reference

https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/naming-the-coronavirus-disease-(covid-2019)-and-the-virus-that-causes-it

31 May 2021

SARS-CoV-2 (French)

1 reference

https://www.who.int/fr/emergencies/diseases/novel-coronavirus-2019/technical-guidance/naming-the-coronavirus-disease-(covid-2019)-and-the-virus-that-causes-it

Office québécois de la langue française

9 November 2021

SRAS-CoV-2 (Canadian French)

named by

1 reference

http://gdt.oqlf.gouv.qc.ca/ficheOqlf.aspx?Id_Fiche=26557605

9 November 2021

SARS-CoV-2 (Arabic)

1 reference

https://www.who.int/ar/emergencies/diseases/novel-coronavirus-2019/technical-guidance/naming-the-coronavirus-disease-(covid-2019)-and-the-virus-that-causes-it

SARS-CoV-2 (Spanish)

1 reference

11 September 2021

https://www.who.int/es/emergencies/diseases/novel-coronavirus-2019/technical-guidance/naming-the-coronavirus-disease-(covid-2019)-and-the-virus-that-causes-it

SRAS-CoV-2 (Russian)

1 reference

https://www.who.int/ru/emergencies/diseases/novel-coronavirus-2019/technical-guidance/naming-the-coronavirus-disease-(covid-2019)-and-the-virus-that-causes-it

9 November 2021

SRAS-CoV-2 (Simplified Chinese)

1 reference

https://www.who.int/zh/emergencies/diseases/novel-coronavirus-2019/technical-guidance/naming-the-coronavirus-disease-(covid-2019)-and-the-virus-that-causes-it

https://ictv.global/msl/current

9 November 2021

taxon name

Severe acute respiratory syndrome-related coronavirus

0 references

0 references

3 references

https://ictv.global/report/chapter/coronaviridae/taxonomy/coronaviridae

The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

taxon common name

severe acute respiratory syndrome coronavirus 2 (English)

2 references

The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

https://ictv.global/report/chapter/coronaviridae/taxonomy/coronaviridae

SARS-CoV-2 (English)

1 reference

https://ictv.global/report/chapter/coronaviridae/taxonomy/coronaviridae

0 references

31 December 2019

5 references

https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200121-sitrep-1-2019-ncov.pdf

Situation Report – 1 (English)

21 January 2020

https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200122-sitrep-2-2019-ncov.pdf

Situation Report – 2 (English)

22 January 2020

https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200123-sitrep-3-2019-ncov.pdf

Situation Report – 3 (English)

23 January 2020

https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200124-sitrep-4-2019-ncov.pdf

Situation Report – 4 (English)

24 January 2020

https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200125-sitrep-5-2019-ncov.pdf

Situation Report – 5 (English)

25 January 2020

time of discovery or invention

COVID-19

0 references

discoverer or inventor

Zhang Jixian

0 references

December 2019

0 references

location of discovery

Wuhan

0 references

genome size

29,903 base pair

2 references

https://www.ebi.ac.uk/ena/data/view/MN908947

24 January 2020

https://www.ncbi.nlm.nih.gov/nuccore/MN908947

physically interacts with

24 January 2020

Transmembrane serine protease 2

2 references

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

The novel coronavirus 2019 (2019-nCoV) uses the SARS-coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells

heparin

1 reference

Characterization of heparin and severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) spike glycoprotein binding interactions

biosafety level

biosafety level 3

2 references

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524674/

https://www.cdc.gov/coronavirus/2019-ncov/lab/lab-biosafety-guidelines.html

quotation

CDC recommends virus isolation in cell culture, and initial characterization of viral agents recovered in cultures of novel SARS-CoV-2 should be conducted in a Biosafety Level 3 (BSL-3) laboratory using BSL-3 practices (English)

fabrication method

natural selection

1 reference

The proximal origin of SARS-CoV-2

Synthetic virology

reason for deprecated rank

unconfirmed hypothesis

not been able to confirm this claim

1 reference

http://virological.org/t/response-to-on-the-origin-and-continuing-evolution-of-sars-cov-2/418

http://virological.org/t/preliminary-phylogenetic-analysis-of-11-ncov2019-genomes-2020-01-19/329

17 March 2020

described at URL

http://virological.org/t/phylogenetic-analysis-of-23-ncov-2019-genomes-2020-01-23/335

English

0 references

English

0 references

hashtag

COVID2019

0 references

SARS-CoV-2

0 references

2019-nCoV

0 references

CoronaVirusWuhan2019

0 references

covid19

0 references

corona

0 references

has natural reservoir

unknown value

1 reference

http://virological.org/t/ncov-2019-codon-usage-and-reservoir-not-snakes-v2/339/4

28 January 2020

Chiroptera

sourcing circumstances

probably

2 references

http://virological.org/t/ncov-2019-codon-usage-and-reservoir-not-snakes-v2/339/4

28 January 2020

https://www.nature.com/articles/s41586-020-2169-0

27 March 2020

Identifying SARS-CoV-2 related coronaviruses in Malayan pangolins

Shamel's Horseshoe Bat

sourcing circumstances

probably

1 reference

https://www.nature.com/articles/d41586-020-03217-0

host

Homo sapiens

2 references

http://virological.org/t/epidemiological-data-from-the-ncov-2019-outbreak-early-descriptions-from-publicly-available-data/337

28 January 2020

https://www.nature.com/articles/s41586-020-2169-0

27 March 2020

Sunda pangolin

2 references

https://www.nature.com/articles/s41586-020-2169-0

27 March 2020

Isolation of SARS-CoV-2-related coronavirus from Malayan pangolins

Felis catus

1 reference

SARS-CoV-2 neutralizing serum antibodies in cats: a serological investigation

Canis familiaris

1 reference

Infection of dogs with SARS-CoV-2

VeroE6/TMPRSS2

2 references

Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells

Vero C1008

1 reference

Caco-2

1 reference

Calu-3

1 reference

HEK293T

1 reference

Huh-7

1 reference

risk group 3 agent (high individual risk, low community risk)

risk group

0 references

ICTV virus genome composition

positive-sense single-stranded RNA virus

0 references

on focus list of Wikimedia project

WikiProject COVID-19

0 references

maintained by WikiProject

WikiProject COVID-19

0 references

entry receptor

angiotensin I converting enzyme 2

3 references

A pneumonia outbreak associated with a new coronavirus of probable bat origin

has contributing factor

Neuropilin 1

https://www.genengnews.com/news/sars-cov-2-uses-a-second-receptor-neuropilin-1-to-infect-human-cells/

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

sequenced genome URL

https://www.ncbi.nlm.nih.gov/nuccore/NC_045512.2

0 references

has part(s)

SARS-Cov-2 genome

1 reference

A new coronavirus associated with human respiratory disease in China

spike glycoprotein [SARS-CoV-2]

1 reference

A new coronavirus associated with human respiratory disease in China

envelope protein [SARS-CoV-2]

1 reference

A new coronavirus associated with human respiratory disease in China

membrane protein [SARS-CoV-2]

1 reference

A new coronavirus associated with human respiratory disease in China

nucleocapsid protein [SARS-CoV-2]

1 reference

A new coronavirus associated with human respiratory disease in China

viral envelope

1 reference

SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography

0 references

1 reference

https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200211-sitrep-22-ncov.pdf

quotation

Following WHO best practices for naming of new human infectious diseases, which were developed in consultation and collaboration with the World Organisation for Animal Health (OIE) and the Food and Agriculture Organization of the United Nations (FAO), WHO has named the disease COVID-19, short for “coronavirus disease 2019.” (English)