Grand Theft Auto IV Walkthrough

Now, your options are numerous here. There are five vans in the area that must be destroyed, and making matters more difficult, the vans can be driven off, effectively eliminating your ability to destroy them and forcing the mission to end in failure. The idea, therefore, is to run around and kill all of the enemies in the area to make sure there are no enemies left to drive those vans. Then, they can be destroyed at your leisure. Enemies are everywhere here, armed with all sorts of various weapons that can cause massive damage and destruction. Utilize cover wisely, and be sure to clear the roofs of the buildings of their numerous enemies as well (there are ladders and a staircase leading up to some of the roofs). From those high vantage points, you should also be able to clear remaining enemies from the high ground if you choose to climb up to them.

When the enemies are severely thinned in numbers (or, better yet, completely eliminated), you can then concentrate on taking out the vans. Naturally, the easiest way to destroy them is by using RPGs or Grenades. If you have either weapon, get into the vans and bunch them together so only one or two rockets or grenades will eliminate them all. Otherwise, if you're without explosives, you can just as easily equip a powerful weapon (we used an Uzi) and pump a clip into the front of each van. A clip should make it start smoking and firing. When that happens, walk away, moving onto the next van, and watching the previous one eventually explode. When the destruction is over, you're in the clear with another completed mission under your belt.