Assassin's Creed 2 Walkthrough

Move toward the open door to the north and a cut scene will show the last remaining guard run away from you. Chase after him, but don't worry if you can't catch him‐it's scripted that you can't. While you're chasing him, a gate will close behind the guard and ahead of you, forcing you to look for an alternate route to the right to circumvent the gate.

You'll catch back up with the runaway guard for more chasing and he'll lead you to the upper level of a large hall. Run up a stack of boxes on the right and from there you can leap out into the open area of the hall and swing across a couple of beams to continue the chase. Another gate ahead locks in front of you. Look to the right and you can climb to a handrail and jump across a series of wooden beams.

The rest of the chase is pretty simple. He'll close another gate in your face, but just turn left to continue following him. When he finally closes a large, stone door behind him, climb up a scaffolding to the right and you can finally confront him (among others).

Don't bother being stealthy here, you'll just have to fight the group of baddies in the large, round room. Play defensively, at least at first, countering incoming attacks with your full-sized sword. When you've whittled down the enemy's numbers, you can start fighting more aggressively to finish them off. After the fight, move down a nearby hall to trigger a cut scene.

As the scene closes, continue down the hall to a room that's loaded with treasure chests. Collect the goods and then open the coffin. There's a door to the right of the coffin that you can open to return to the streets of Florence.