Saying what I say about how you can never have enough robots fighting monsters, or monster fighting robots, or gorillas fighting zombies, I think it's safe to say there's nothing wrong with Big Bruisers fighting any and all of the above.
http://www.comicbookresources.com/?page=article&id=22177
Of course I'm Johnny on the Spot for this as well. Phil Hester is a pretty solid talent, writing or drawing, so I'm there.