Biochemistry: Concepts and Connections (2nd Edition)
Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 5, Problem 12P

a. Write a possible sequence for an mRNA segment coding for apamine.
b. Do you think apamine is synthesized in the form shown in Problem 11, or is it more likely a product of proteolytic cleavage of a larger peptide? Explain.

11. Apamine is a small protein toxin present in the venom of the honeybee. It has the sequence
CNCKAPETALCARRCQQH
a. If apamine does not react with iodoacetate (see Tools of Biochemistry 5B), then how many disulfide bonds are present?
b. If trypsin cleavage gave two peptides, then where is(are) the S-S bond(s)?

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8. AMINE OR AMIDE Compound a. Nicotinamide Draw the Structure and Identify in the structure which is the Amide or Amine functional Group b. Histamine c. Oxytocin Biomedical Use/ Function II. Draw, explain the following IUPAC name is incorrect and then write the correct IUPAC name. a. 2-Ethyl-1-propene b. 1,6-Dibromo-6-methyloctane c. 4-methyl-4-hexene d. 6,6-Dimethylcyclohexene
III. Name the following compounds using IUPAC Naming a. b. OH CH3 NH2 Preferred IUPAC: Aniline Systematic IUPAC Benzenamine NH2 d. H3C e. OH CH-CH-CH-CH-CH₂ CH f. IV. Guide Questions: 1. What are alkyl halides and its uses? Common Names: :: phenyla benzam
2. ALDEHYDE Compound Draw the Structure and Identify in the structure which is the Aldehyde functional group a. Glucose b. Glyceraldehyde c. Acetaldehyde 3. ALCOHOL Biomedical Use/ Function Compound Draw the Structure and Identify in the structure which is the Alcohol functional Group Biomedical Use/ Function a. Glycerol b. Sorbitol C. Ribose 4. CARBOXYLIC ACID Compound a. Pyruvate b. Niacin C. Lactic Acid Draw the Structure and Identify in Biomedical Use/ Function the structure which is the Carboxylic Acid functional Group BIOCHEMISTRY LABORATORY MANUAL | 13
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