VLC has hardware decoding on most platforms. It supports 0-copy on the GPU and can fallback on software when required.
MPEG-1/2, DivX® (1/2/3/4/5/6), MPEG-4 ASP, XviD, 3ivX D4, H.261, H.263 / H.263i, H.264 / MPEG-4 AVC, Cinepak, Theora, Dirac / VC-2, MJPEG (A/B), WMV 1/2, WMV 3 / WMV-9 / VC-1, Sorenson 1/3, DV, On2 VP3/VP5/VP6, Indeo Video v3 (IV32), Real Video (1/2/3/4).
MPEG Layer 1/2, MP3 - MPEG Layer 3, AAC - MPEG-4 part3, Vorbis, AC3 - A/52, E-AC-3, MLP / TrueHD>3, DTS, WMA 1/2, WMA 3, FLAC, ALAC, Speex, Musepack / MPC, ATRAC 3, Wavpack, Mod, TrueAudio, APE, Real Audio, Alaw/µlaw, AMR (3GPP), MIDI, LPCM, ADPCM, QCELP, DV Audio, QDM2/QDMC, MACE.
DVD, Text files (MicroDVD, SubRIP, SubViewer, SSA1-5, SAMI, VPlayer), Closed captions, Vobsub, Universal Subtitle Format (USF), SVCD / CVD, DVB, OGM, CMML, Kate.
ID3 tags, APEv2, Vorbis comment.
VLC has the most complete feature-set over the video, subtitle synchronisation, video and audio filters.
UDP/RTP Unicast, UDP/RTP Multicast, HTTP / FTP, MMS, TCP/RTP Unicast, DCCP/RTP Unicast, File, DVD Video, Video CD / VCD, SVCD, Audio CD (no DTS-CD), DVB (Satellite, Digital TV, Cable TV), MPEG encoder, Video acquisition.
MPEG (ES,PS,TS,PVA,MP3), AVI, ASF / WMV / WMA, MP4 / MOV / 3GP, OGG / OGM / Annodex, Matroska (MKV), Real, WAV (including DTS), Raw Audio: DTS, AAC, AC3/A52, Raw DV, FLAC, FLV (Flash), MXF, Nut, Standard MIDI / SMF, Creative™ Voice.
SAP/SDP announces, Bonjour protocol, Mozilla/Firefox plugin, ActiveX plugin, SVCD Menus, Localization, CD-Text, CDDB CD info, IGMPv3, IPv6, MLDv2, CPU acceleration.