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Identification of Depression Subtypes Based on EEG and Machine Learning

Published: 11 April 2022 Publication History

Abstract

Depressive disorders are heterogeneous in symptoms and course of disease, while it is difficult to reveal the neurophysiological subtypes. In this study, we combined EEG data and machine learning methods to identify subtypes of depression, and further evaluated the rationality and reliability of subtypes. The results showed that the left-right asymmetry of prefrontal lobe in alpha band clustered 32 patients with depression into three different subtypes, each type showed unique clinical characteristics. High classification effects could be obtained through decision tree and logistic regression model. The study further investigated the new way to identify neurophysiological subtypes of depression with machine learning methods. This study also shows the important value of the classic EEG index of depression, namely the left-right asymmetry of prefrontal lobe in alpha band, in the identification of depression subtypes.

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  • (2023)Technical and clinical considerations for electroencephalography-based biomarkers for major depressive disordernpj Mental Health Research10.1038/s44184-023-00038-72:1Online publication date: 25-Oct-2023
  1. Identification of Depression Subtypes Based on EEG and Machine Learning

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    cover image ACM Conferences
    WI-IAT '21: IEEE/WIC/ACM International Conference on Web Intelligence and Intelligent Agent Technology
    December 2021
    541 pages
    ISBN:9781450391870
    DOI:10.1145/3498851
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    Published: 11 April 2022

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    Author Tags

    1. Cluster analysis
    2. Decision tree
    3. Depression subtype
    4. EEG
    5. Logistic regression model

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    WI-IAT '21: IEEE/WIC/ACM International Conference on Web Intelligence
    December 14 - 17, 2021
    VIC, Melbourne, Australia

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    • (2023)Technical and clinical considerations for electroencephalography-based biomarkers for major depressive disordernpj Mental Health Research10.1038/s44184-023-00038-72:1Online publication date: 25-Oct-2023

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