H2HUB: Hybrid Hub: Cellular and computation models, micro- and nano-technologies for personalized innovative therapies
Details
Funded by: Ministero della Salute - Piano Operativo Salute - Traiettoria 4 “Biotecnologia, bioinformatica e sviluppo farmaceutico"
Reference: POS T4 H2HUB
Start: 2023-03-01
Duration: 48 months
Partners
Coordinator: IRCCS Giannina Gaslini
Italy
Contractor: CRS4
Italy
Contractor: UNIGE
Italy
Contractor: UNICA
Italy
Contractor: ARNAS G. Brotzu
Italy
Contractor: AOU Cagliari
Italy
Contractor: AORN Moscati
Italy
Abstract
H2UB is intended to be a Life Science infrastructure aimed at fostering new drug development through a network of laboratories capable of providing basic, translational and preclinical research support using cutting-edge technologies. Governance of the Hub will be centralized and will provide support in regulatory, ethics and management, as well as organizational and dissemination. Expertise will be articulated in thematic platforms that will include: basic research (biobanks of iPS and organoids as models of pathology; identification of specific molecular targets; fabrication of bio-electronic systems for drug evaluation); pre-clinical research (animal models, identification and validation of disease biomarkers through computational data analysis, pharmacodynamics); new drug development (manufacturing, safety monitoring, specificity and formulation); clinical consulting.
CRS4 Visual and Data-intensive Computing activities target the study, development and application of scalable pipelines for data analysis and of tools to support digital pathology.
Main offices:
Visual Computing Group
CRS4
Ex-Distilleria, Via Ampere 2
09134 Cagliari (CA), ITALY
Secondary offices:
Visual Computing Group
CRS4
Sardegna Ricerche Edificio 1
C.P. 25
09010 Pula (CA), ITALY