The primary purpose of the Scientist II, in Process Science, designs, evaluates and develops the suitable rAAV formulation to support the growing and diversifying portfolio of programs within AGT’s pipeline. S/he is also responsible for product-related development, such as device compatibility, container-closure selection and tech transfer to GMP team. S/he partners with other internal stakeholders as required to identify new CMC technologies and assess external landscape for potential collaboration or other engagement. S/he collaborates with all team members and stakeholders to develop his/her own and their human and technical skills as well as to ensure activities are adequately proceeded and key milestones are achieved.
Develop suitable formulation for each serotype, including engineered capsids, with appropriate analytical tools
Conceive and conduct device compatibility for ensuring injected amounts
Evaluate and assess new container-closure for local injection products
Lead the technical discussion cross-functional/divisional to be aligned and enable to proceed with drug development works appropriately and efficiently
Evaluate and understand analytical tools and methods deeply enable to develop rAAV formulation appropriately
Create and evaluate novel and innovative technology applicable to drug development for AAV product
S/he participates the program meeting to achieve key milestones with timely manner
Regularly presents data and conclusions in sub-team meetings
Occasionally presents technology summaries to management and program teams
（変更の範囲）
会社内での全ての業務
【就業環境に関する要件 / Specific Physical or Environmental Requirements】
On-site (Tsukuba in Japan)
【応募要件 / Qualifications】
＜必須 / Must＞
Advanced degree in biology or engineering with 8+ years of relevant biopharmaceutical industry experience
Experience of formulation development and/or drug product development for biopharmaceutical products
Experience working with external vendors, institutions, and other collaborators to develop and/or evaluate new and disruptive technologies
Experience operation of basic analytical tools, such as chromatography and electrophoresis
Proven and successful history of taking direction and work independently in a fast paced environment
Positive, professional attitude with a passion for science
Outstanding collaboration, problem solving team player with excellent communication and organizational skills
Business English level
＜歓迎 / Want＞
Prior rAAV gene therapy vector or other viral particle experience
Prior fill-finish experience
Experience with authoring IND, CTA, and other related regulatory filings and responding to Agency feedback/inquiries
Experience with tech transfer into GMP facilities/labs
【応募書類 / Application Documents】
和文履歴書・和文職務経歴書・英文レジュメ
Both Japanese and English Resumes are needed
【選考プロセス / Selection details】
書類選考 → 1次面接 → 適性検査 → 最終面接
※変更の可能性もございますので、予めご了承下さい。
CV screening → First interview → Aptitude test → Final interview
Please be advised that there might be a change in the process.
【勤務地 / Location】
（雇入れ直後）
茨城県つくば市 アステラス製薬 つくば研究センター
Tsukuba, Ibaraki
※ＪＲひたち野うしく駅とつくばエクスプレス（TX) 研究学園駅より通勤バスがございます。
（変更の範囲）
会社の定める事業場および自宅
【勤務開始日 / Start Date】
応相談
Will be decided according to the candidate's flexibility
【契約期間 / Contract Duration】
期間の定めなし
Not limited to specified period
【試用期間 / Probation Period】
試用期間原則なし
No probation period in principle
【給与 / Salary】
①基本給：当人の経歴・技術・技能等を考慮して決定
②裁量労働制の場合：裁量労働手当として職務グレードに応じて50,000～100,000円支給
①Base salary: will be decided by the candidate's experience, skill and capability.
②When Discretionary Work System is applied: Discretionary work allowance will be paid.(50,000～100,000yen, based on the Grade)
【昇給 / Salary Raise】
有り
【賞与 / Bonus】
有り
【諸手当 / Allowance】
裁量労働手当、住宅手当、通勤手当 等
Discretionary work allowance, Housing allowance, Commutation allowance, etc.
【勤務時間 / Working Hours】
8:30～17:30（月～木）、8:30～15:45（金）、専門業務型 裁量労働制
裁量労働制の場合、所定労働時間を働いたものとみなす。
8:30～17:30（Mon～Thu）、8:30～15:45（Fri）
Discretionary Work System
【休日 / Holidays】
完全週休２日制（土曜・日曜）、祝日、5月1日、夏季、年末年始
Weekends(Sat and Sun), holidays, May 1st, summer vacation, New Year holidays
【休暇 / Vacation Leave】
年次有給休暇、育児休業制度、介護休業制度 等
Annual paid leave, childcare leave system, nursing care leave system, etc.
【福利厚生 / Welfare】
雇用保険、労災保険、厚生年金、健康保険、共済会制度、社宅制度、持株会制度、財形貯蓄制度 等
Employment Insurance, Industrial Accident Compensation Insurance, Welfare Pension Insurance, Health Insurance, Mutual Aid Association System, Company Housing System, Employee Shareholder Association System, Property Accumulation Savings System
For more information about Astellas, please visit our career web site.
"We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law."