Mycobacterium tuberculosis - Wikipedia
Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. [1] [2] First discovered in 1882 by Robert Koch, M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid.
Tuberculosis (TB) | Definition, Cause, Symptoms, & Treatment
3 days ago · tuberculosis (TB), infectious disease that is caused by the tubercle bacillus, Mycobacterium tuberculosis. In most forms of the disease , the bacillus spreads slowly and widely in the lungs , causing the formation of hard nodules (tubercles) or large cheeselike masses that break down the respiratory tissues and form cavities in the lungs.
Tuberculosis - Wikipedia
Koch announced a glycerine extract of the tubercle bacilli as a "remedy" for tuberculosis in 1890, calling it "tuberculin". Although it was not effective, it was later successfully adapted as a screening test for the presence of pre-symptomatic tuberculosis. [ 38 ]
Clinical Overview of Tuberculosis | Tuberculosis (TB) | CDC
Oct 30, 2024 · M. tuberculosis organisms are also called tubercle bacilli or TB bacteria. TB bacteria usually attack the lungs but can attack any part of the body such as the kidney, spine, and brain. TB can also affect multiple parts of the body at the same time.
The Biology of Mycobacterium Tuberculosis Infection - PMC
Mtb infection occurs when few tubercle bacilli dispersed in the air from a patient with active pulmonary TB reach the alveoli of the host.
Clinical Overview of Tuberculosis Disease - CDC
Dec 10, 2024 · TB disease occurs when tubercle bacilli overwhelm the immune system of someone with latent TB infection and multiply. If a person is infected with TB bacteria, and the immune system cannot keep the tubercle bacilli under control, the bacilli will multiply rapidly, causing TB disease.
Tuberculosis - StatPearls - NCBI Bookshelf
Aug 11, 2024 · Tuberculosis is aerobic, non–spore-forming, and nonmotile bacilli. The uniquely high concentration of lipids in the cell wall makes the bacilli acid-fast staining and likely contributes to immunomodulation and virulence.
Tuberculosis and the Tubercle Bacillus - PMC - PubMed Central …
Tuberculosis and the Tubercle Bacillus has many contributors; chapters are provided by experts in many areas of TB research to bring together a comprehensive update of research development in the past decade.
Tuberculosis (TB) - Infectious Diseases - MSD Manual Professional Edition
The first step in sputum examination is typically microscopic examination to check for acid-fast bacilli (AFB). Tubercle bacilli are nominally gram-positive but take up Gram stain inconsistently; samples are best prepared with Ziehl-Neelsen or Kinyoun stains for conventional light microscopy or fluorochrome stains for the more sensitive ...
Infection occurs when a person inhales droplet nuclei containing tubercle bacilli that reach the alveoli of the lungs. These tubercle bacilli are ingested by alveolar macrophages. While most bacilli are destroyed or inhibited, a small number may multiply intracellularly and be released when the macrophages die. If alive, these