Tretinoin - StatPearls - NCBI Bookshelf
Mar 27, 2023 · Tretinoin is a valuable medication in treating mild, moderate, and severe acne that can be used topically or systemically. Tretinoin is also used systemically in the management of acute promyelocytic leukemia (APL). Tretinoin is a vitamin A derivate in …
Tretinoin: Uses, Interactions, Mechanism of Action | DrugBank ...
Tretinoin is a vitamin A derivative used to treat acne vulgaris and certain types of promyelocytic leukemia, as well as various skin conditions in over-the-counter medications.
Tretinoin - Wikipedia
Tretinoin, also known as all-trans retinoic acid (ATRA), is a medication used for the treatment of acne and acute promyelocytic leukemia. [ 8 ] [ 9 ] [ 10 ] For acne, it is applied to the skin as a cream, gel or ointment. [ 10 ]
A Clinician’s Guide to Topical Retinoids - PMC
Tretinoin (All-trans retinoic acid) is the first topical retinoid to be developed. Tretinoin is indicated in the treatment of acne vulgaris and photoaging/rhytides.
Why Topical Retinoids Are Mainstay of Therapy for Acne - PMC
Jun 17, 2024 · The efficacy of individual topical retinoids increases with increasing concentration. Tretinoin was first shown to have dose-dependent effects in animal models . In two separate ultra-structural studies, 12 weeks of tretinoin therapy (0.1% and 0.025%) reduced microcomedones by 80% and 35%, respectively [18, 25].
Retinoids: active molecules influencing skin structure ...
Tretinoin (all trans-retinoic acid) is the most bioactive form among retinoids applied topically to the skin. Tretinoin increases the epidermal cellular turnover, it also causes dispersion of melanin granules.
Tretinoin | C20H28O2 | CID 444795 - PubChem
The exact mechanism of action of tretinoin in skin conditions and acute promyelocytic leukemia (APL) has not been fully elucidated; however, several proposed mechanisms exist.