STAT1 - 维基百科，自由的百科全书
stat1是转录因子中信号转导及转录激活蛋白（stat蛋白）家族的一员。 STAT1涉及 I型 、 II型 或 III型 干扰素 激活基因的正调控。
STAT1 - Wikipedia
Signal transducer and activator of transcription 1 (STAT1) is a transcription factor which in humans is encoded by the STAT1 gene. It is a member of the STAT protein family. [5]
STAT1 - 百度百科
信号转导与转录激活因子 1 ( signal transducerand activator of transcription 1， STAT1) 是一种连接 细胞膜受体 与效应器间信号传导的重要蛋白。胞质中的 STAT1 在胞外信号的刺激作用下可发生磷酸 化并聚合形成同源或异源二聚体， 继而进入胞核促进靶基因转录 。
STAT（信号传导及转录激活蛋白）_百度百科
当stat被磷酸化后，发生聚合成为同源或异源二聚体形式的活化的转录激活因子，进入胞核内与靶基因启动子序列的特定位点结合，促进其转录。已克隆成功4种jak(jak13和tyk2)与7种stat(stat1，stat2，stat3，stat4，stat5a，stat5b，stat6)。
STAT1 Gene - GeneCards | STAT1 Protein | STAT1 Antibody
Dec 10, 2024 · Complete information for STAT1 gene (Protein Coding), Signal Transducer And Activator Of Transcription 1, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium
30岁了！ CELL重磅综述：JAK-STAT通路全面解读！ - 健康界
Nov 14, 2022 · 1、stat1-gof患者易患自身免疫性疾病，对真菌和病毒感染的易感性增加； 小鼠和人类的stat2 lof突变导致了对病毒的易感性增加。 2、stat3的lof突变是高免疫球蛋白 e（乔布氏）综合征的分子基础。
The JAK/STAT signaling pathway: from bench to clinic
Nov 26, 2021 · The signal transduction and activator of transcription (STAT) family have six members: STAT1 (STAT1 has two splicing isoforms, STAT1α and STAT1β), STAT2, STAT3 (STAT3 has two splicing isoforms...
信号转导及转录激活蛋白 - 维基百科，自由的百科全书
在哺乳动物基因组中已发现七个stat家族成员，分别是： stat1、stat2、stat3、stat4、stat5（stat5a和stat5b）以及stat6。 STAT1同源二聚体参与 II型干扰素 引发的信号通路，进入细胞核后会结合到 GAS （ Interferon- G amma A ctivated S equence ， 干扰素γ 激活序列）启动子，激活 ISG ...
STAT1 signal transducer and activator of transcription 1 [ (human)]
STAT1 is associated with giant cell tumor of bone recurrence, which might serve as biomarker for giant cell tumor of bone recurrence; High STAT1 expression is associated with head and neck squamous cell carcinoma.
Complex roles of Stat1 in regulating gene expression
May 25, 2000 · Stat1 is a fascinating and complex protein with multiple, yet contrasting transcriptional functions. Upon activation, it drives the expression of many genes but also suppresses the transcription...