A Patient of Multiple Myeloma with Absent M-spike on Serum …
Multiple myeloma is a consequence of abnormal plasma cell proliferation in the bone marrow and accounts for 10% of the hematological malignancies, hence it is uncommon. SPEP remains a …
Tests for Multiple Myeloma | American Cancer Society
It is done to look for myeloma or light chain amyloidosis. This is most helpful in the rare cases of myeloma in which no M protein is found by SPEP. Since the SPEP measures the levels of …
Non-Secretory Myeloma or Light Chain-Producing Multiple Myeloma…
Nonsecretory multiple myeloma (NSMM) is a rare variant of the classic form of MM that has a similar clinical and radiologic presentation except for the absence of the M-protein in serum …
In most patients with MM, large amounts of an abnormal immunoglobulin protein (M-spike) will appear as a large peak on the graph. Immunofixation is done to identify the specific type of …
A Patient of Multiple Myeloma with Absent M-spike on Serum
Aug 16, 2019 · Here, we report a rare presentation of multiple myeloma with normal serum protein electrophoresis but elevated serum-free light chains. The absence of monoclonal gammopathy …
Multiple myeloma - Diagnosis and treatment - Mayo Clinic
Dec 20, 2024 · When multiple myeloma causes symptoms, treatment often starts with medicine. Treatment can help relieve pain, control complications, and slow the growth of the myeloma …
Understanding and Interpreting Serum Protein Electrophoresis
Jan 1, 2005 · Serum protein electrophoresis is a laboratory examination that commonly is used to identify patients with multiple myeloma and other disorders of serum protein. Many …
M Protein (Myeloma Protein): Definition, Test, and Levels - WebMD
Oct 12, 2024 · To check if you have a cancer called multiple myeloma, your doctor may ask you to get a test for M protein. If M protein shows up in your blood or urine, it's a sign you might …
When a Monoclonal Gammopathy Is Not Multiple Myeloma
Apr 8, 2022 · Monoclonal gammopathies represent a broad differential diagnosis and require a thorough evaluation for clinical significance. Smoldering multiple myeloma is a clinical entity …
Multiple Myeloma | Diagnosis of Multiple Myeloma | LLS
If present, an excessive production of a monoclonal immunoglobulin may be shown in laboratory test results as a spike on a graph (M spike). Most patients with untreated myeloma have a …
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