Integrin - Wikipedia
Integrin subunits span the cell membrane and have short cytoplasmic domains of 40–70 amino acids. The exception is the beta-4 subunit, which has a cytoplasmic domain of 1,088 amino acids, one of the largest of any membrane protein.
整联蛋白 - 百度百科
整联蛋白（integrin）又称整合素，整联蛋白属整合蛋白家族，是一类普遍存在于脊椎动物细胞表面，依赖于Ca2+或Mg2+的异亲型细胞黏附分子，介导细胞和细胞之间以及细胞和细胞外基质之间的相互识别和粘附，具有联系细胞外部作用与细胞内部结构的作用。
整合素 - 维基百科，自由的百科全书
整合素（英語： Integrin ）又稱整联蛋白、接合蛋白，是一种介导细胞和其外环境（如细胞外基质，Extra Cellular Matrix）之间的连接的跨膜受体，普遍存在于脊椎动物的細胞表面。
Integrins: An Overview of Structural and Functional Aspects
Furthermore, integrin-mediated adhesion modulates signaling cascades in control of cell motility, survival, proliferation, and differentiation. Here, a brief overview of basic structure/function aspects of integrins is given with the aim of providing background …
肿瘤治疗又一“成会玩”的靶点，Integrin凭什么？ - 知乎
Feb 22, 2021 · Integrin是什么？ Integrin是由α（120~185kD）和β（90~110kD）两个亚单位形成的异二聚体跨膜糖蛋白，迄今已发现约18种α亚单位和8种 β亚单位 ，它们按不同的组合构成20余种功能不同的Integrin分子。
Targeting integrin pathways: mechanisms and advances in …
Jan 2, 2023 · Integrin functions are dependable on a delicate balance between active and inactive status via multiple mechanisms, including protein-protein interactions, conformational changes,...
integrin 信号通路 - 知乎 - 知乎专栏
整联蛋白（integrin）又称整合素，普遍存在于脊椎动物细胞表面，依赖于Ca2+或Mg2+的异亲型 细胞黏附分子 ，介导细胞和细胞之间以及细胞和 细胞外基质 之间的相互识别和粘附，具有联系细胞外部作用与细胞内部结构的作用。
Integrins - Molecular Biology of the Cell - NCBI Bookshelf
An integrin molecule is composed of two noncovalently associated transmembrane glycoprotein subunits called α and β (Figure 19-64; see also Figure 19-12B). Because the same integrin molecule in different cell types can have different ligand -binding specificities, it seems that additional cell-type-specific factors can interact with integrins ...
Integrin Structure, Activation, and Interactions - PMC
Integrins are large, membrane-spanning, heterodimeric proteins that are essential for a metazoan existence. All members of the integrin family adopt a shape that resembles a large “head” on two “legs,” with the head containing the sites for ligand ...
Integrins - PMC
Integrins are cell adhesion receptors that are evolutionary old and that play important roles during developmental and pathological processes. The integrin family is composed of 24 αβ heterodimeric members that mediate the attachment of cells to the ...