Dec 24, 2024 · DKK1 (Dickkopf WNT Signaling Pathway Inhibitor 1) is a Protein Coding gene. Diseases associated with DKK1 include Chiari Malformation Type I and Osteoporosis, …

Dickkopf-1 (Dkk1) is a secretory antagonist of the classical Wnt signaling pathway. Many studies have reported that Dkk1 is abnormally expressed in tumor cells, and abnormal expression of …

Clinical studies in a range of cancers have detected elevated levels of the Wnt antagonist Dickkopf-1 (DKK1) in the serum or tumors of patients, and this was frequently associated with …

Jan 4, 2025 · DKK1 is a novel target gene in the response to amino acid deficiency and that the expression of DKK1 is up-regulated through an ATF4-independent and an ERK-dependent …

Sep 20, 2004 · Through computational screening and subsequent experimental analysis, we identified a novel TCF target gene, DKK1, which has been shown to be a potent inhibitor of …

Dickkopf-1 (DKK1) is a well-characterized Wnt inhibitor and component of the Wnt/β-catenin signaling pathway, whose dysregulation is associated with multiple abnormal pathologies …

Dec 4, 2006 · Dickkopf (Dkk) genes comprise an evolutionary conserved small gene family of four members (Dkk1 - 4) and a unique Dkk3 -related gene, Dkkl1 (soggy). They encode secreted …

May 1, 2022 · Dickkopf1 (DKK1) was originally identified as a secreted protein that antagonizes Wnt signaling. Although DKK1 is essential for the developmental process, its functions in …

4 days ago · A DKK1 serum levels were measured by ELISA in no tumor-bearing (NTB) 6–8 weeks old C57BL/6 WT female mice (n = 5) or 2 weeks after the inoculation of PyMT-BO1 …

Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity (By similarity). We now provide the "Disease & Variants" viewer in its own …