NGS has many advantages for miRNA profiling. It is a fast, reliable and cost-effective technique to analyse both the expression and sequence of miRNAs in any tissue or sample type, even if they ...
The amplification step is unavoidable in current deep sequencing protocols, but microarrays often skip amplification in favor of directly labeling microRNA. This labeling step introduces much of ...
The significance of degradome sequencing lies in its ability to provide a more accurate and reliable identification of miRNA target genes compared to traditional bioinformatics predictions. By ...
RNAs in plants and cnidarian animals operate similarly by binding their targets with nearly-full complementarity, in contrast ...
Nobel Prize microRNA discovery started with a tiny roundworm This Nobel Prize is all about foundational genetics. At the heart of what makes a living organism function is the ability of double ...
outlining cutting-edge research that is identifying new miRNA targets. He’ll also discuss the latest methodologies in miRNA research, including next-generation sequencing and miRNA inhibition.