New research has suggested that a simple and 'relatively cheap' supplement or diet could be the key to improving cancer ...

Researchers have identified the protein MYO1F as a key regulator of T-cell metabolism, with implications for immune responses ...

Findings reveal that metabolic enzymes ACSS2 and ACLY regulate T cell exhaustion, linking nutrient metabolism to epigenetic ...

A new paper from MUSC Hollings Cancer Center researchers is helping to reveal the "rules" for engineering chimeric antigen ...

Suppression by inhibitory cytokines: interleukin-10 (IL-10), transforming growth factor-β (TGFβ) and the newly identified IL-35 are key mediators of T Reg-cell function. Although they are all ...

The novel link between nutrition and cell identity offers a new explanation for exhausted T cell identity and in turn, offers ...

A simple dietary supplement may provide a new approach to boost CAR T cell function, according to a new study.

As it turns out, the healthy function of the Golgi apparatus has a lot to do with how well T-cells function in killing cancer cells. Understanding how a signaling axis mitigates Golgi stress ...

Filamin proteins are degraded by ASB2α E3 ubiquitin ligase and may affect T cell function. Here the authors show that increased levels of Filamin A and Filamin B in Th2 cells reduces allergic ...

In vivo, tumor-bearing mice that had the HIF1α-deleted in T cells did not respond to ICB therapy. The researchers then showed ...