Cocaine affects mitochondrial function in a number of ways—altering electron transport, production of reactive oxygen species and oxidative stress, mitochondrial dynamics, and mitophagy.

As a result, ROS from overactive mitochondria are frequently cited as a source of DNA damage. Despite this longstanding belief, few studies have explicitly demonstrated this linkage. Tobias Dansen, a ...

Using bulk-RNA sequencing to study mice with macrophages deficient in mitochondria ETC complex III, the scientists discovered that a type of reactive oxygen species (ROS), or unstable molecules ...

“While the live mice emit robust UPE, likely indicative of ongoing biological processes and cellular activity, the dead ...

There’s another interesting property of mtDNA that makes it useful in ancestry studies. Because mitochondrial genome is exposed to reactive oxygen species and possesses less efficient repair ...

Mitochondria are responsible for producing and providing energy to our bodies, especially in organs such as the heart, brain, and muscles, which require high-energy production. These organs ...