Research that focused on blocking the renin-angiotensin system (RAS) led to the discovery of ACE inhibitors, which proved efficacious in the treatment of hypertension, various cardiovascular ...

Teams of researchers are investigating empagliflozin and dapagliflozin in patients with autosomal dominant polycystic kidney ...

A reasonable strategy would be to stop the ACE inhibitor and start a diuretic. If the renin level is high, then it might be reasonable to add either a ß blocker or an angiotensin receptor antagonist.

Now that they know the cause, researchers say the next step is to figure out how to use the effective blood pressure drugs known as renin-angiotensin system inhibitors—often called RAS ...

Inhibition of the renin–angiotensin system using either an angiotensin-converting-enzyme (ACE) inhibitor or an angiotensin-receptor blocker (ARB) effectively decreases rates of urinary protein ...

A study from the University of Virginia suggests that long-term use of certain medications commonly prescribed for high blood ...

The dual-action agent LCZ696 blocks the angiotensin II receptor (via a valsartan moiety) and inhibits neprilysin (via an AHU377 moiety). In a phase II trial, this drug “demonstrated superior ...