Polygenic scores, like so many human traits, are normally distributed, meaning they follow the pattern of the bell curve.

The spread of possible SightScore results is shown as a ‘bell curve,’ with most people near the middle, ... As the first truly polygenic clinical genetic risk score for glaucoma on the ...

Genome-wide polygenic scores (GPSs) can identify individuals at high risk for coronary artery disease (CAD), atrial fibrillation (AF), type 2 diabetes, chronic inflammatory bowel disease (IBD ...

In the ALSPAC cohort, the polygenic risk score was able to identify children who developed short stature in adulthood with an area under the receiver operating characteristic curve (AUROC) of 0.84 ...

The best-fit model for predicting any (area under the curve [AUC], 0.69) and clinically significant (AUC, 0.78) prostate cancer included age, family history, PSA, and PI-RADS.