Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon. Neuron , 2020; DOI: 10.1016/j.neuron.2020.06.036 Cite This Page : ...

The study, “Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon,” published in Neuron, identifies a mechanism the researchers say is triggered at ...

identifies a mechanism the researchers say is triggered at neuron birth to intrinsically decrease a general form of cell death — or “apoptosis” — specifically in neurons. When this genetic regulation ...

Neuronal apoptosis, or programmed cell death, underlies many neurodegenerative diseases, including Alzheimer and Parkinson disease. If scientists could measure and track this phenomenon, they could ...

This method of triggering a single neuron’s death, which the researchers have dubbed “2Phatal,” allowed for the initiation of apoptosis without causing the death of surrounding cells.

Moreover, caspase inhibitors significantly attenuate ischaemic neuronal injury. Although there is strong evidence for apoptosis in ischaemic brain injury, not all cells die by apoptosis.

axonal transport, and ubiquitin−proteasome system were disrupted by this pollutant. These effects ultimately lead to neurodegeneration through neuronal apoptosis and cell death.

Second, what are the triggers for necroptosis and what is its physiological role in relation to apoptosis? In non-neuronal cells, necroptosis may serve as a back-up mechanism to eliminate cells when ...

When our neurons—the principle cells of the brain—die, so do we. A research team led by Sika Zheng, a biomedical scientist at the University of California, Riverside, has challenged this ...

RIVERSIDE, Calif. -- When our neurons -- the principal cells of the brain -- die, so do we. Most neurons are created during embryonic development and have no "backup" after birth. Researchers have ...