Alzheimer’s disease may cause degeneration of neurons in the brain through amyloid plaques, neurofibrillary tangles, inflammation, and brain atrophy. The condition may affect different parts of ...

The tissue abnormalities first defined by Alzheimer as clumps and tangles among neurons in the cortex are more specifically defined as amyloid plaques and neurofibrillary tangles. Plaques are ...

The full spectrum of gene expression regulation associated with many neurodegenerative diseases, including Alzheimer’s, is ...

Instead of performing its normal function, tau builds up inside neurons and forms twisted clumps, called neurofibrillary tangles. These tangles can disrupt communication between neurons.

Over the course of years or decades in this preclinical stage, the characteristic buildup of disease-causing amyloid plaques ...

Researchers optimized portable low-field MRI with machine learning to improve brain morphometry and white matter ...

Yet, in those with Alzheimer’s disease, tau appears to behave abnormally in the brain by building up inside and forming twisted clumps, called neurofibrillary tangles, which disrupt ...

Despite decades of starts and stops, new treatments and key genetic discoveries are giving researchers great hope for slowing or eventually preventing Alzheimer’s disease.