WEST PALM BEACH, Florida — A comprehensive multiomics analysis of a 6-month phase 2 trial of a ketogenic diet in multiple sclerosis (MS) confirmed significant anti-inflammatory effects, aligning ...

Evotec International GmbH has divulged NLRP3 inflammasome inhibitors reported to be useful for the treatment of asthma, cryopyrin-associated periodic syndromes, hypertension, Alzheimer’s disease, ...

Gum disease caused by the bacteria Porphyromonas gingivalis is linked to worse multiple sclerosis (MS) in a mouse model of ...

The experimental ALS treatment usnoflast exhibited promising signs of slowed functional decline and improved breathing in a ...

The NLRP3 inflammasome constitutes an intracellular complex of multiple proteins that promote caspase1 autocatalysis and the consequent maturation and production of the proinflammatory cytokines ...

Denali Therapeutics Inc. has disclosed NLRP3 inflammasome inhibitors reported to be useful for the treatment of stroke, gout, multiple sclerosis, Alzheimer's disease, hypertension, silicosis, ...

The potential for NLRP3 inhibitors extends beyond autoimmune and inflammatory diseases. ... and multiple sclerosis, as well as metabolic conditions like gout and non-alcoholic steatohepatitis ...

The efficacy of Usnoflast has been established in several pre-clinical models of neuroinflammation, Parkinson’s disease, Inflammatory Bowel Disease (IBD) and Multiple Sclerosis (MS).

Scientists have uncovered the structures of NLRP1, NLRP3, NLRC4, and AIM2 molecules. In the case of the Human NLRP1 gene, multiple alternatively spliced transcript variants that encode up to five ...

Jupiter, Florida, Jan. 13, 2025 (GLOBE NEWSWIRE) -- Jupiter Neurosciences, Inc. (NASDAQ: JUNS) (“Jupiter” or the “Company”), a clinical-stage pharmaceutical company developing JOTROL™, a ...