Multiple endocrine neoplasia type 1 (MEN1) is a hereditary tumor syndrome characterized by tumors of the parathyroid glands, the pancreatic islets, the pituitary gland, the adrenal glands ...

1995). In 1997, loss of heterozygosity (LOH) on chromosome 11q13 was reported in pituitary adenomas of 2 siblings with familial acromegaly. This locus comprised the MEN1 gene, so it was suggested that ...