A research team at the University of Osaka has unveiled the molecular mechanism behind genome ejection from adeno-associated ...

For more details, take a look at C.M. Fouletier-Dilling et al. 2005, Human Gene Therapy, 16:1287–1297. Adenovirus 5 is an important vector because it can infect a variety of non-dividing cells and ...

AAV is a useful vector for delivering genes; however, the size of the gene that can be carried is limited. Therefore, Dr. Kamiya and his team constructed a base editing tool (SaCas9-NNG-ABE8e ...

Thomas LeJolly, Asia-Pacific (APAC) director at Polyplus, also sees vector production as the core issue. “The main challenges in gene therapy viral vector manufacturing come from the complexity ...

The company also claims its platform can be used for rapid clinical development of cell and gene therapies and can be scaled for commercialization of these products. Vector BioMed was co-founded ...

The U.S. Food and Drug Administration (FDA) granted platform technology designation to the viral vector used in SRP-9003, an ...

Investigators headed by a team at Brigham and Women’s Hospital have developed an adeno-associated virus (AAV) vector that studies ... to being able to deliver gene therapy across the blood ...