The resultant succinic semialdehyde undergoes further metabolism to either GABA or succinate. A mitochondrial NADP +-independent transhydrogenase is capable of metabolizing GHB to succinic ...

To find out, the researchers chemically blocked the metabolism of ketamine. This prevented formation of the metabolite, which blocked the drug's antidepressant-like effects. Like ketamine ...

They're not. Both 1,4-butanediol (BDO) and gamma-butyrolactone (GBL) are pro-drugs of GHB; they have no pharmacological activity until your body metabolizes them. Here is the one-step enzymatic ...

GHB is a natural product of human metabolism, which means that it is synthesised when food is broken down and turned into energy for our cells. The compound is also found in our diet: animal meat ...

Following his conviction for 159 sex offences, Home Secretary Priti Patel called for a review of controls for drugs like GHB. What is GHB? Although it is sometimes referred to as a date rape drug ...

Jazz Pharmaceuticals brought in more than $1.7 billion last year selling GHB to narcolepsy patients. With the new approval, sales could soar. By Virginia Hughes In the 1960s, the drug was given to ...

Even succinic acid, a product of GHB metabolism, becomes undetectable in urine within hours of ingestion. However, the GHB in the body of a crime victim is still present, even after it has been ...