The Irf8 floxed mouse strain can be used to ... could be used to help define patterns of gene expression important for the development and function of cells including possible contributions ...

has developed a comprehensive set of innovative genetic tools and mouse lines, called iFlpMosaics, designed to enhance the study of gene function and its implications in health and disease.

Researchers can switch genes on and off in the genome of the mouse precisely and at specific times in the development process and then study the effects. This allows conclusions to be drawn about the ...