Researchers at the National Human Genome Research Institute have discovered a new inflammatory disorder called vacuoles, E1 enzyme, X-linked, autoinflammatory and somatic syndrome (VEXAS), which ...

Ubiquitin and other ubiquitin-like molecules (UBLs) are post-translationally attached to proteins through a sequential enzymatic cascade that uses an E1 activating enzyme, an E2 conjugating enzyme ...

Small ubiquitin-related modifier (SUMO) — which is attached to proteins by a pathway involving the E1 enzyme SAE1, the E2 enzyme UBC9 (also known as UBE21) and an E3 ligase (such as PIAS1 and ...