Scientists have unlocked new details on important receptor proteins—promising targets for the creation of novel drugs for ...

Scientists have unlocked new details on important ‘receptor’ proteins –promising targets for the creation of novel drugs for ...

Researchers have identified a new receptor complex in the brain that responds to several types of antipsychotic drugs used to treat schizophrenia and also reacts to hallucinogenic drugs such as LSD.

The new findings help explain why some drugs that interact with these receptors have had unexpectedly complex and sometimes harmful effects. A team including scientists from The Scripps Research ...

The funds will support Phase 2 testing of a drug the company believes to be able to safety home in on AMPA receptors, an ...

One in every three FDA-approved drugs targets a single superfamily of receptors dotting the surfaces of human cells. From beta blockers to antihistamines, these essential, life-saving medications ...

which targets large numbers of G-protein coupled receptors (GPCRs) and their downstream signaling pathways to engineer drugs to treat complex diseases. Additionally, Octant is responding to the ...

“We found that D1 receptor antagonists—drugs that block D1 receptors from ... They found that D1 and D2 bound to each other to form a complex (heteromer). When activated by DA, this heteromer ...

researchers determined the receptor's structure in different states, including when it's inactive, partially active, and fully active. They also examined how it interacts with specific drugs that ...

“GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling.” “These super-complexes or 'megaplexes' more readily form at receptors that interact strongly with β ...

They all belong to a class of drugs known as glucagon-like peptide-1 receptor agonists (GLP-1RAs ... it’s not a magic formula — there are complex considerations such as dosages, costs ...