Human liver UDP-glucuronosyltransferases (UGTs) are a crucial family of enzymes involved in drug metabolism. They play a significant role in the biotransformation of various substances ...

Scientists have unveiled a groundbreaking method to test how thousands of active substances influence cellular metabolism ...

A new study from the Kowalinski group at EMBL Grenoble characterized the structure of an important trypanosomal protein ...

Antibiotics are a double-edged sword—they should be as toxic as possible to pathogenic bacteria while being harmless to the cells of the human body. An international research team led by the Helmholtz ...

A comprehensive new study supports evidence of the myriad health benefits of GLP-1 medications like Ozempic and Mounjaro — ...

The new molecules target a metabolic pathway that only occurs in bacterial cells, thus sparing human cells. The team ...

Researchers at the University of Basel are able to test in parallel the effects of over 1,500 active substances on cell ...

Scientists have developed a new strategy to enhance pharmaceutical production in Chinese hamster ovary (CHO) cells, which are commonly used to manufacture protein-based drugs for treating cancer, ...

Antibiotics are a double-edged sword – they should be as toxic as possible to pathogenic bacteria while being harmless to the cells of the human body. An international research team led by the ...

The MEP pathway is an essential part of the energy metabolism ... example by a drug, the bacteria can no longer produce a number of vital natural products and subsequently die. Human cells do ...