Steady-state plasma concentration is reached in 10 days. Gefitinib is a pregnancy category D medication, indicating probable harm to the fetus. It is eliminated by metabolism through the CYP3A4 ...

Tyrosine kinase inhibitors (TKIs) are a class of targeted cancer therapies designed to block the action of tyrosine kinases, enzymes that play a key role in cellular functions such as growth, division ...

Cisbio's HTRF® KinEASE™ assay for screening serine/threonine kinases now extends to tyrosine kinases (TK). The assay, developed in partnership with Millipore, uses a unique substrate containing ...