There are two main hypotheses for the cause of exercise related osteoarthritis: wear and tear of the articular cartilage and muscle dysfunction ... Institutes of Health Research and the Canadian ...

Damage to articular cartilage (cartilage covering the ends of bones where they meet in a joint) frequently occurs due to injury or illness, and can lead to degenerative disease. Treatments and ...

Osteoarthritis, which is also the most common type of arthritis, develops when the articular cartilage in a joint starts to break down, changing the bone. Articular cartilage is the soft lining of ...

The pathology of the disease process often leads to the destruction of articular cartilage and ankylosis of the joints. Rheumatoid arthritis can also produce diffuse inflammation in the lungs ...

based on research from his lab now published in Arthritis & Rheumatism. Articular cartilage erosion is a characteristic feature of osteoarthritis (OA) and, at present, no drugs that inhibit this ...

Restoration of the diseased articular cartilage in patients ... is the development of gene-based therapies for arthritis and the regeneration of cartilage, ligament and tendon defects.

compared with moderate evidence of a cartilage defect prevalence of 12% (95% CI 7% to 21%) in asymptomatic individuals. Conclusion The prevalence of intra-articular hip pathologies is highly variable ...