Although apoptosis has been well defined, alternative forms of cell death have been less explored. In my lab, we performed a global analysis of pharmacologically accessible cell death mechanisms using ...

Without enough cystine, lipid peroxidation can trigger a form of ... and ultimately cell death. Inhibitors of apoptosis, ferroptosis and other cell death mechanisms had no effect on this process ...

By around 2000, apoptosis had become the prominent mode ... antioxidant depletion or acute iron overload. Reevaluating Lipid Peroxidation and Oxidative Stress The relationship between LPO and ...

apoptosis, autophagy, necrosis, necroptosis and pyroptosis. In 2012, a study revealed a unique form of cell death, termed ferroptosis, that is dependent on iron and unregulated lipid peroxidation.