3d). Unique interactions exploited by MKC9989 ... for enhanced potency of MKC9989 relative to OICR464 and OICR573. The aldehyde moiety of HAA inhibitors has been shown to selectively form a ...

But it’s difficult to produce aldehydes in Escherichia coli because the bacteria have many enzymes that reduce aldehydes to alcohols. Researchers previously have made aliphatic aldehydes by ...

Focusing on DPCs caused by aldehyde, the scientists used a method called DPC-seq to investigate the link between aldehyde accumulation and DNA damage in premature-aging disease patients.

A team of researchers at Nagoya University in Japan has discovered that aldehydes are metabolic byproducts associated with premature aging. Published in Nature Cell Biology, their findings reveal ...

Aldehydes contained in edible oils of a very different nature after prolonged heating at frying temperature: Presence of toxic oxygenated α,β unsaturated aldehydes. Food Chemistry , 2012; 131 (3 ...

Researchers from the University of the Basque Country (UPV/EHU, Spain) have been the first to discover the presence of certain aldehydes in food, which are believed to be related to some ...

A team of researchers at Nagoya University in Japan has discovered that aldehydes are metabolic byproducts associated with premature aging. Published in Nature Cell Biology, their findings reveal ...

By pinpointing aldehydes as substances that contribute to aging, this study sheds light on the intricate connection between environmental factors and cellular aging. This may have significant ...