Matrine Manufacturer

1. Matrine Overview

Matrine is an alkaloid made from dried roots of legume Sophora flavescens by organic solvent extraction. It is used to treat eczema and dermatitis, because of its antibacterial and anti-inflammatory effects. Moreover, matrine has a promoting effect on collagen production and the proliferation of fibroblasts; so it can be used as an anti-aging agent on the skin. The main effect of matrine on the skin is anti-allergic; it can be used for the treatment of skin itching caused by skin diseases such as eczema or urticaria, and other skin diseases such as allergic dermatitis. Therefore, matrine can be applied in anti-acne, anti-inflammation and other functional skincare products.

Product Name	CAS Number	INCI Name
Matrine	519-02-8	SOPHORA FLAVESCENS ROOT EXTRACT
Molecular Weight	Molecular Formula	Molecular Structure
C15H24N2O	248.37g/mol
Product ID	Specificcation	Minimal Package	Minimal Order Quantity
PMQD0402	98%	1KG	1KG

2. Matrine Source

Sophora flavescens is distributed in Russia, Japan, India, North Korea, and other provinces in the north and south of China. It grows at an altitude of 1,500 meters and is mostly found on hillsides, sandy land, grass slopes, shrubs and fields. Chinese medicine believes that Sophora flavescens has the effects of clearing away heat and dampness, killing insects and diuresis.

3. Matrine Manufacturer Specifications 

4. Matrine Benefits

• Anti-inflammation

Matrine regulates the body’s immune response (differentiation of Th17 cells). Also, it inhibits the release of inflammatory mediators, thereby inhibits the inflammatory response of skin lesions, and effectively inhibits IgE cross-linking and the release of histamine, leukotrienes and other transmitters.  Matrine can stabilize cell membranes and exert anti-inflammation effect for skincare.

• Anti-bacterial

Modern pharmacology shows that matrine inhibits the release of P. acnes and bacterial outer membrane vesicles. Additionally, it can inhibit a variety of bacilli, streptococcus b and Staphylococcus aureus in vitro to varying degrees, as well as a variety of dermatophytes. Thus, matrine can treat acne and pimple.

5. Pharmacological Study of Matrine and Cosmetics

6. Plamed Matrine Characteristics

• Plamed uses high-quality dried roots of Sophora flavescensas raw material, which can guarantee matrine’s high purity and good quality.
• Plamed matrine has good water solubility and light color.

7. Matrine Application & Dosage

Matrine is mainly applied in anti-acne, anti-inflammation skin care products. It is also can be added into tooth care products, as well as hair care products.

Application examples of matrine in cosmetic brands:

8. Matrine Safety

• Cosmetic, Toiletry & Fragrance Association (CTFA) has specified SOPHORA FLAVESCENS ROOT EXTRACT as a cosmetics ingredient.
• SOPHORA FLAVESCENS ROOT EXTRACT is included in The International Catalogue of Chinese Cosmetic Raw Materials Standards in 2010 issued by CAFFCI
• SOPHORA FLAVESCENS ROOT EXTRACT is listed On the Announcement of Name List of Cosmetics Raw Material published by CFDA in 2021. No reports show its insecurity.

9. Matrine Reference Formula

Anti-inflammation cream

10. Related Reading

1. Oxymatrine: Sophora Angustifolia Extract for Skin Care

2. Oxymatrine Introduction

Plamed focuses on natural cosmetic ingredients for more than 10 years. We have founded four subsidiary companies, which respectively develops different kinds of cosmetic raw material. Plamed is a company whose CEO is designated as the first secretary general of Shaanxi Plant Extraction Association.

As a professional matrine manufacturer, Plamed have been constantly upgrading the production process. We firmly believe that good matrine and good matrine price will help customers make good terminal products and help customers win a lasting and broad market.